Evidence map›Paper›PMID 32532199›Full record

Observational studyBMC cardiovascular disorders2020

Population attributable risk estimates of risk factors for contrast-induced acute kidney injury following coronary angiography: a cohort study.

Li Lei, Yan Xue, Zhaodong Guo, Bowen Liu, Yibo He, Feier Song, Jin Liu, Guoli Sun, Liling Chen, Kaihong Chen and 8 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 1 country.

Li LeiThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China.
Yan XueDepartment of Cardiology, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Zhaodong GuoDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated Guangdong Provincial People's Hospital of South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China.
Bowen LiuGuangdong Provincial People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Yibo HeDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated Guangdong Provincial People's Hospital of South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China.
Feier SongDepartment of Emergency and Critical Care Medicine, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou, Guangdong, China.
Jin LiuDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated Guangdong Provincial People's Hospital of South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China.
Guoli SunDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated Guangdong Provincial People's Hospital of South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China.
Liling ChenDepartment of Cardiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, 364000, Fujian, China.
Kaihong ChenDepartment of Cardiology, Longyan First Affiliated Hospital of Fujian Medical University, Longyan, 364000, Fujian, China.
Zhiqi SuDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated Guangdong Provincial People's Hospital of South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China.
Li PanDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated Guangdong Provincial People's Hospital of South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China.
Zhidong HuangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Yulu HuangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Xiuqiong HuangSchool of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong, China.
Shiqun ChenDepartment of Cardiology, Provincial Key Laboratory of Coronary Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Affiliated Guangdong Provincial People's Hospital of South China University of Technology, Guangdong Academy of Medical Sciences, Guangzhou, 510080, Guangdong, China.
Jiyan ChenThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China. chenjiyandr@126.com.
Yong LiuThe Second School of Clinical Medicine, Southern Medical University, Guangzhou, 510515, Guangdong, China. liuyong@gdph.org.cn.ORCID 0000-0003-2224-4885
Guangdong Academy of Medical Sciences · CNGuangdong Pharmaceutical University · CNFujian Medical University · CNSecond Affiliated Hospital of Guangzhou Medical University · CNGuangdong Provincial People's Hospital · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CN

Funding

Beijing Lisheng Cardiovascular Pilot Foundation LHJJ201612127"Lixin Yangfan" Optimized Anti-thrombus Research Fund BJUHFCSOARF201801-10The Access Research Fund 2018-CCA-AF-037The China Youth Clinical Research Fund 2017-CCA-VG-020The Progress in Science and Technology Project of Guangzhou 201904010470
6 · The paper itself

Abstract

backgroundContrast-induced acute kidney injury (CI-AKI) is a common complication with poor outcomes following coronary angiography (CAG) or percutaneous coronary intervention (PCI). However, no study has explored the population attributable risks (PARs) of the CI-AKI risk factors. Therefore, we aimed to identify the independent risk factors of CI-AKI and estimate their PARs.

methodsWe analyzed 3450 consecutive patients undergoing CAG/PCI from a prospective cohort in Guangdong Provincial People's Hospital. CI-AKI was defined as a serum creatinine elevation ≥50% or 0.3 mg/dL from baseline within the first 48 to 72 h after the procedure. Independent risk factors for CI-AKI were evaluated through stepwise approach and multivariable logistic regression analysis, and those that are potentially modifiable were of interest. PARs of independent risk factors were calculated with their odds ratios and prevalence among our cohort.

resultsThe overall incidence of CI-AKI was 7.19% (n = 248), which was associated with increased long-term mortality. Independent risk factors for CI-AKI included heart failure (HF) symptoms, hypoalbuminemia, high contrast volume, hypotension, hypertension, chronic kidney disease stages, acute myocardial infarction and age > 75 years. Among the four risk factors of interest, the PAR of HF symptoms was the highest (38.06%), followed by hypoalbuminemia (17.69%), high contrast volume (12.91%) and hypotension (4.21%).

conclusionsThese modifiable risk factors (e.g., HF symptoms, hypoalbuminemia) could be important and cost-effective targets for prevention and treatment strategies to reduce the risk of CI-AKI. Intervention studies targeting these risk factors are needed.

Indexed as

Acute Kidney InjuryAgedAged, 80 and overBiomarkersChinaContrast MediaCoronary AngiographyCoronary Artery DiseaseCreatinineFemaleHeart FailureHumansHypoalbuminemiaHypotensionIncidenceMaleBiomarkersContrast MediaCreatinineAcute renal diseaseCatheterizationPopulation attributable riskRisk factors

Identifiers

PMID32532199
PMCPMC7291532
OpenAlexW3035256901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.