Evidence map›Paper›PMID 32532105›Full record

ArticleCancers2020

Copy Number Alterations of Depressed Colorectal Neoplasm Predict the Survival and Response to Oxaliplatin in Proximal Colon Cancer.

Li-Chun Chang, Han-Mo Chiu, Bing-Ching Ho, Min-Hsuan Chen, Yin-Chen Hsu, Wei-Tzu Chiu, Kang-Yi Su, Chia-Tung Shun, Jin-Tung Liang, Sung-Liang Yu and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Li-Chun ChangDepartment of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.
Han-Mo ChiuDepartment of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.
Bing-Ching HoCenters of Genomic and Precision Medicine, National Taiwan University, Taipei 100, Taiwan.
Min-Hsuan ChenCenters of Genomic and Precision Medicine, National Taiwan University, Taipei 100, Taiwan.
Yin-Chen HsuDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0003-2478-9037
Wei-Tzu ChiuDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Kang-Yi SuDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0002-6538-9526
Chia-Tung ShunDepartment of Pathology and Forensic Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.
Jin-Tung LiangDepartment of Surgery, National Taiwan University Hospital, Taipei 100, Taiwan.
Sung-Liang YuGraduate Institute of Clinical Medicine, National Taiwan University College of Medicine, Taipei 100, Taiwan.
Ming-Shiang WuDepartment of Internal Medicine, National Taiwan University Hospital, Taipei 100, Taiwan.
National Taiwan University · TWNational Taiwan University Hospital · TW

Funding

Ministry of Science and Technology, Taiwan MOST-105-2314-B-002-047
6 · The paper itself

Abstract

Depressed colorectal neoplasm exhibits high malignant potential and shows rapid invasiveness. We investigated the genomic profile of depressed neoplasms and clarified the survival outcome and treatment response of the cancers arising from them. We examined 20 depressed and 13 polypoid neoplasms by genome-wide copy number analysis. Subsequently, we validated the identified copy number alterations (CNAs) in an independent cohort of 37 depressed and 42 polypoid neoplasms. Finally, the CNAs were tested as biomarkers in 530 colorectal cancers (CRCs) to clarify the clinical outcome of depressed neoplasms. CNAs in

Indexed as

BIRC7CCNA1chemotherapyCNAscolorectal cancerMYC

Identifiers

PMID32532105
PMCPMC7352996
OpenAlexW3035609930

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.