Evidence map›Paper›PMID 32532079›Full record

ReviewInternational journal of molecular sciences2020

Association Between Celiac Disease and Cancer.

Irene Marafini, Giovanni Monteleone, Carmine Stolfi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Colonic neoplasia and celiac disease: A systematic review.World journal of gastroenterology · 2025
    Pooled it
  2. Pancreatic Cancer in Celiac Disease Patients-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
    Pooled it
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  9. Unusual Location of a Rare Complication of Celiac Disease.GE Portuguese journal of gastroenterology · 2025
    Article
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  15. The link between gluten intake and the risk of cancers.Gastroenterology and hepatology from bed to bench · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Irene MarafiniDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Giovanni MonteleoneDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.
Carmine StolfiDepartment of Systems Medicine, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-6354-2443

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is a chronic enteropathy that develops in genetically susceptible individuals after the ingestion of gluten. There has been a substantial increase in CD prevalence in the last 50 years, and it is now estimated that this disease affects approximately 1% of the population in the Western world. In the large majority of cases, CD is a benign disease, characterized by the complete resolution of symptoms and a normal life expectancy after the onset of a gluten-free diet (GFD). However, failure to adhere to a strict GFD bears the risk of adverse events and increases mortality. A considerable number of studies have considered the possible association between CD and neoplasms. In particular, an increased risk of malignancies, such as cancers of the gastrointestinal tract and intestinal lymphomas, has been reported. In this review, we summarize and discuss the current evidence on the possible association between CD and cancer.

Indexed as

Celiac DiseaseDiet, Gluten-FreeGastrointestinal NeoplasmsHumansLymphoproliferative DisordersNeoplasmscolorectal cancerglutengluten-free dietHLA-DQ2HLA-DQ8refractory celiac diseasesmall bowel adenocarcinomaT-cell lymphoma

Identifiers

PMID32532079
PMCPMC7312081

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.