Evidence map›Paper›PMID 32531940›Full record

ArticleInternational journal of molecular sciences2020

Protective Effect of Alpha-Lipoic Acid on Salivary Dysfunction in a Mouse Model of Radioiodine Therapy-Induced Sialoadenitis.

Jung Hwa Jung, Jin Hyun Kim, Myeong Hee Jung, Seung Won Kim, Bae Kwon Jeong, Seung Hoon Woo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jung Hwa JungDepartment of Internal medicine, Gyeongsang National University School of Medicine and Gyeongsang National University Hospital, Jinju 52727, Korea.ORCID 0000-0001-6285-8262
Jin Hyun KimInstitute of Health Science, Gyeongsang National University School of Medicine, Jinju 52727, Korea.ORCID 0000-0003-2913-6481
Myeong Hee JungBiomedical Research Institute, Gyeongsang National University Hospital, Jinju 52727, Korea.
Seung Won KimAnimal Molecular Imaging Team, Research Core Center, National Cancer Center, Goyang 10408, Korea.
Bae Kwon JeongInstitute of Health Science, Gyeongsang National University School of Medicine, Jinju 52727, Korea.ORCID 0000-0001-8015-6061
Seung Hoon WooDepartment of Otorhinolaryngology-Head and Neck Surgery, Dankook University, Cheonan 31116, Korea.
Gyeongsang National University · KRDankook University · KRGyeongsang National University Hospital · KRNational Cancer Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radioiodine (RI) therapy is known to cause salivary gland (SG) dysfunction. The effects of antioxidants on RI-induced SG damage have not been well described. This study was performed to investigate the radioprotective effects of alpha lipoic acid (ALA) administered prior to RI therapy in a mouse model of RI-induced sialadenitis. Four-week-old female C57BL/6 mice were divided into four groups (

Indexed as

AnimalsApoptosisAquaporin 5Body WeightCellular SenescenceEnzyme-Linked Immunosorbent AssayFemaleIodine RadioisotopesMice, Inbred C57BLRadiation Injuries, ExperimentalRadiation-Protective AgentsRadiotherapySalivaSalivary GlandsSialadenitisThioctic AcidAqp5 protein, mouseAquaporin 5Iodine RadioisotopesRadiation-Protective AgentsThioctic Acidalpha lipoic acidcomplicationsRIsalivary glandThyroid

Identifiers

PMID32531940
PMCPMC7312690
OpenAlexW3035313240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.