Evidence map›Paper›PMID 32531928›Full record

ReviewCells2020

The Role of Single-Cell Technology in the Study and Control of Infectious Diseases.

Weikang Nicholas Lin, Matthew Zirui Tay, Ri Lu, Yi Liu, Chia-Hung Chen, Lih Feng Cheow

Abstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Optimized single-cell gates for yeast display screening.Protein engineering, design & selection : PEDS · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Transcriptome Architecture of Osteoblastic Cells Infected WithFrontiers in cellular and infection microbiology · 2022
    Article
  12. Review
  13. Pathogen detection with electrochemical biosensors: Advantages, challenges and future perspectives.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2021
    Review
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weikang Nicholas LinDepartment of Biomedical Engineering, National University of Singapore, Singapore 119007, Singapore.
Matthew Zirui TaySingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A∗STAR), Singapore 138648, Singapore.
Ri LuNUS Graduate School for Integrated Sciences and Engineering, Singapore 119007, Singapore.
Yi LiuDepartment of Biomedical Engineering, National University of Singapore, Singapore 119007, Singapore.
Chia-Hung ChenDepartment of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon Tong 999077, Hong Kong SAR, China.
Lih Feng CheowDepartment of Biomedical Engineering, National University of Singapore, Singapore 119007, Singapore.ORCID 0000-0003-1766-0024

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of single-cell research in the recent decade has allowed biological studies at an unprecedented resolution and scale. In particular, single-cell analysis techniques such as Next-Generation Sequencing (NGS) and Fluorescence-Activated Cell Sorting (FACS) have helped show substantial links between cellular heterogeneity and infectious disease progression. The extensive characterization of genomic and phenotypic biomarkers, in addition to host-pathogen interactions at the single-cell level, has resulted in the discovery of previously unknown infection mechanisms as well as potential treatment options. In this article, we review the various single-cell technologies and their applications in the ongoing fight against infectious diseases, as well as discuss the potential opportunities for future development.

Indexed as

Communicable DiseasesHumansSingle-Cell Analysisdiagnosticsinfectious diseasepathophysiologysingle celltherapeutics

Identifiers

PMID32531928
PMCPMC7348906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.