ArticleMolecular ecology resources2020
Genomic basis of environmental adaptation in the leathery sea squirt (Styela clava).
Article in Molecular ecology resources, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 38 citations in OpenAlex.
- Identification of protein precursor for thyroid hormone synthesis in basal chordate ascidian Styela clava.Nature communications · 2026Article
- Germline de novo mutation rate of the highly heterozygous amphioxus genome.Molecular biology and evolution · 2026Article
- De novo genome assembly, inversion detection, and worldwide adaptation on the invasive species Styela plicata.Scientific reports · 2025Article
- Transcriptome Analysis Reveals the Requirement of the TGFβ Pathway in Ascidian Tail Regression.Cells · 2025Article
- First chromosome-level genome assembly of the colonial chordate model Botryllus schlosseri (Tunicata).GigaScience · 2025Article
- Morphological Characteristics, Mitochondrial Genome, and Evolutionary Insights Into a New Sea Squirt From the Beibu Gulf.Ecology and evolution · 2025Article
- Spatially resolved single-cell atlas of ascidian endostyle provides insight into the origin of vertebrate pharyngeal organs.Science advances · 2024Article
- Temporospatial hierarchy and allele-specific expression of zygotic genome activation revealed by distant interspecific urochordate hybrids.Nature communications · 2024Article
- Genomic Resources and Annotations for a Colonial Ascidian, the Light-Bulb Sea Squirt Clavelina lepadiformis.Genome biology and evolution · 2024Article
- Establishment of a developmental atlas and transgenetic tools in the ascidianMarine life science & technology · 2023Article
- Transcriptional Analysis of the Endostyle Reveals Pharyngeal Organ Functions in Ascidian.Biology · 2023Article
- Thyroid-like hormone signaling in invertebrates and its potential role in initial screening of thyroid hormone system disrupting chemicals.Integrated environmental assessment and management · 2023Review
- Article
- Cultivation of gut microorganisms of the marine ascidianMarine life science & technology · 2022Article
- The Genome of the "Sea Vomit"Life (Basel, Switzerland) · 2021Article
- Genome-Wide Identification, Comparison, and Expression Analysis of Transcription Factors in AscidianInternational journal of molecular sciences · 2021Article
- Genomic basis of environmental adaptation in the leathery sea squirt (Styela clava).Molecular ecology resources · 2020Article
- Seasonal dynamics and starvation impact on the gut microbiome of urochordate ascidian Halocynthia roretzi.Animal microbiome · 2020Article
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
Abstract
Tunicates occupy the evolutionary position at the boundary of invertebrates and vertebrates. It exhibits adaptation to broad environmental conditions and is distributed globally. Despite hundreds of years of embryogenesis studies, the genetic basis of the invasive habits of ascidians remains largely unknown. The leathery sea squirt, Styela clava, is an important invasive species. We used the chromosomal-level genome and transcriptome of S. clava to explore its genomic- and molecular-network-based mechanisms of adaptation to environments. Compared with Ciona intestinalis type A (C. robusta), the size of the S. clava genome was expanded by 2-fold, although the gene number was comparable. An increase in transposon number and variation in dominant types were identified as potential expansion mechanisms. In the S. clava genome, the number of genes encoding the heat-shock protein 70 family and members of the complement system was expanded significantly, and cold-shock protein genes were transferred horizontally into the S. clava genome from bacteria. The expanded gene families potentially play roles in the adaptation of S. clava to its environments. The loss of key genes in the galactan synthesis pathway might explain the distinct tunic structure and hardness compared with the ascidian Ciona species. We demonstrated further that the integrated thyroid hormone pathway participated in the regulation of larval metamorphosis that provides S. clava with two opportunities for adapting to their environment. Thus, our report of the chromosomal-level leathery sea squirt genome provides a comprehensive genomic basis for the understanding of environmental adaptation in tunicates.
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