ArticleCurrent biology : CB2020
Zebrafish Retinal Ganglion Cells Asymmetrically Encode Spectral and Temporal Information across Visual Space.
Article in Current biology : CB, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
43 citing papers in PubMed, 86 citations in OpenAlex.
- Development of the zebrafish foveal analogue: a quantitative atlas of high-acuity zone growth and retinal regionalisation.Biology open · 2026Article
- Genome-wide association and multi-omics functional screens reveal the genetic architecture of foveal development.medRxiv : the preprint server for health sciences · 2026Article
- MARINER: a surround visual stimulator for vision research in aquatic animals.bioRxiv : the preprint server for biology · 2026Article
- A heterogeneous population code at the first synapse of vision.Nature communications · 2026Article
- Loss of retinal stem cell reserve and lipofuscin accumulation accelerates cone-rod degeneration and replicates Stargardt disease in abca4b null zebrafish.Scientific reports · 2025Article
- Artificial embodied circuits uncover neural architectures of vertebrate visuomotor behaviors.Science robotics · 2025Article
- Exceptional Visual-Opsin Coexpression and Phenotypic Diversity in Outer-Retinal Photoreceptors of Caenophidian Snakes.The Journal of comparative neurology · 2025Article
- Zebrafish optic nerve injury results in systemic retinal ganglion cell dedifferentiation.PLoS genetics · 2025Article
- Quantifying the link between retinal performance and the optomotor response.Current biology : CB · 2025Article
- On analogies in vertebrate and insect visual systems.Nature reviews. Neuroscience · 2025Review
- Task-specific regional circuit adaptations in distinct mouse retinal ganglion cells.Science advances · 2025Article
- Article
- Ontogeny of Thyroid Hormone Signaling in the Retina of Zebrafish: Effects of Thyroidal Status on Retinal Morphology, Cell Survival, and Color Preference.International journal of molecular sciences · 2024Article
- Article
- A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regeneration.Development (Cambridge, England) · 2024Article
- Light wavelength modulates search behavior performance in zebrafish.Scientific reports · 2024Article
- Ancient origin of the rod bipolar cell pathway in the vertebrate retina.Nature ecology & evolution · 2024Article
- The vertebrate retina: a window into the evolution of computation in the brain.Current opinion in behavioral sciences · 2024Review
- Asymmetric distribution of color-opponent response types across mouse visual cortex supports superior color vision in the sky.bioRxiv : the preprint server for biology · 2024Article
- Transcriptional control of visual neural circuit development by GS homeobox 1.PLoS genetics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 3 countries.
Funding
Abstract
In vertebrate vision, the tetrachromatic larval zebrafish permits non-invasive monitoring and manipulating of neural activity across the nervous system in vivo during ongoing behavior. However, despite a perhaps unparalleled understanding of links between zebrafish brain circuits and visual behaviors, comparatively little is known about what their eyes send to the brain via retinal ganglion cells (RGCs). Major gaps in knowledge include any information on spectral coding and information on potentially critical variations in RGC properties across the retinal surface corresponding with asymmetries in the statistics of natural visual space and behavioral demands. Here, we use in vivo two-photon imaging during hyperspectral visual stimulation as well as photolabeling of RGCs to provide a functional and anatomical census of RGCs in larval zebrafish. We find that RGCs' functional and structural properties differ across the eye and include a notable population of UV-responsive On-sustained RGCs that are only found in the acute zone, likely to support visual prey capture of UV-bright zooplankton. Next, approximately half of RGCs display diverse forms of color opponency, including many that are driven by a pervasive and slow blue-Off system-far in excess of what would be required to satisfy traditional models of color vision. In addition, most information on spectral contrast was intermixed with temporal information. Taken together, our results suggest that zebrafish RGCs send a diverse and highly regionalized time-color code to the brain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.