ArticlePloS one2020
Lights triggered differential accumulation of antioxidant and antidiabetic secondary metabolites in callus culture of Eclipta alba L.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Exploring the impact of light spectra on growth: unveiling the role of LED light in modulating phytochemical responses of feverfew (Tanacetum parthenium L.).BMC plant biology · 2026Article
- Red and Far-Red LED Lighting Enhances Protoplast-to-Plant Regeneration in Broccoli (Plants (Basel, Switzerland) · 2026Article
- OptimizingPlants (Basel, Switzerland) · 2025Article
- A Network Pharmacology Study and In Vitro Evaluation of the Bioactive Compounds ofMolecules (Basel, Switzerland) · 2025Article
- LED light improves shoot multiplication, steviol glycosides and phenolic compounds biosynthesis in Stevia rebaudiana Bertoni in vitro culture.Scientific reports · 2024Article
- The Effect of Combined Elicitation with Light and Temperature on the Chlorogenic Acid Content, Total Phenolic Content and Antioxidant Activity ofPlants (Basel, Switzerland) · 2024Article
- Production of Polyphenolic Natural Products by Bract-Derived Tissue Cultures of Three MedicinalPlants (Basel, Switzerland) · 2024Article
- Co-cultures from Plants and Cyanobacteria: A New Way for Production Systems in Agriculture and Bioprocess Engineering.Advances in biochemical engineering/biotechnology · 2024Review
- Trends in the Tissue Culture Techniques and the Synthesis of Bioactive Compounds inPlants (Basel, Switzerland) · 2023Review
- Effect of Wide-Spectrum Monochromatic Lights on Growth, Phytochemistry, Nutraceuticals, and Antioxidant Potential of In Vitro Callus Cultures ofMolecules (Basel, Switzerland) · 2023Article
- Influence of Plant Growth Regulators and Artificial Light on the Growth and Accumulation of Inulin of Dedifferentiated Chicory (Life (Basel, Switzerland) · 2022Article
- Differential Flavonoid and Other Phenolic Accumulations and Antioxidant Activities ofMolecules (Basel, Switzerland) · 2022Article
- Beyond vegetables: effects of indoor LED light on specialized metabolite biosynthesis in medicinal and aromatic plants, edible flowers, and microgreens.Journal of the science of food and agriculture · 2022Review
- Effect of Traditional Cooking and In Vitro Gastrointestinal Digestion of the Ten Most Consumed Beans from the Fabaceae Family in Thailand on Their Phytochemicals, Antioxidant and Anti-Diabetic Potentials.Plants (Basel, Switzerland) · 2021Article
- Sustainable and efficient protocols for in vitro germination and antioxidants production from seeds of the endangered species Araucaria araucana.Journal, genetic engineering & biotechnology · 2021Article
- Review
- Phytochemical Profile, α-Glucosidase, and α-Amylase Inhibition Potential and Toxicity Evaluation of Extracts fromBiomolecules · 2021Article
- Linking the Phytochemicals and the α-Glucosidase and α-Amylase Enzyme Inhibitory Effects ofFoods (Basel, Switzerland) · 2021Article
- Scarlet FlaxMolecules (Basel, Switzerland) · 2021Article
- Comparative Effects of Different Light Sources on the Production of Key Secondary Metabolites in Plants In Vitro Cultures.Plants (Basel, Switzerland) · 2021Review
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9 authors.
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Abstract
Eclipta alba L., also known as false daisy, is well known and commercially attractive plant with excellent hepatotoxic and antidiabetic activities. Light is considered a key modulator in plant morphogenesis and survival by regulating important physiological cascades. Current study was carried out to investigate growth and developmental aspects of E. alba under differential effect of multispectral lights. In vitro derived callus culture of E. alba was exposed to multispectral monochromatic lights under controlled aseptic conditions. Maximum dry weight was recorded in culture grown under red light (11.2 g/L) whereas negative effect was observed under exposure of yellow light on callus growth (4.87 g/L). Furthermore, red light significantly enhanced phenolics and flavonoids content (TPC: 57.8 mg/g, TFC: 11.1 mg/g) in callus cultures compared to rest of lights. HPLC analysis further confirmed highest accumulation of four major compounds i.e. coumarin (1.26 mg/g), eclalbatin (5.00 mg/g), wedelolactone (32.54 mg/g) and demethylwedelolactone (23.67 mg/g) and two minor compounds (β-amyrin: 0.38 mg/g, luteolin: 0.39 mg/g) in red light treated culture whereas stigmasterol was found optimum (0.22 mg/g) under blue light. In vitro based biological activities including antioxidant, antidiabetic and lipase inhibitory assays showed optimum values in cultures exposed to red light, suggesting crucial role of these phytochemicals in the enhancement of the therapeutic potential of E. alba. These results clearly revealed that the use of multispectral lights in in vitro cultures could be an effective strategy for enhanced production of phytochemicals.
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