Evidence map›Paper›PMID 32530573›Full record

SynthesisDiagnostic cytopathology2020

Automated classification of cancer from fine needle aspiration cytological image use neural networks: A meta-analysis.

Jian Huang, Dongcun Wang, Jiping Da

Abstract readMeta-Analysis
In one paragraph

Synthesis in Diagnostic cytopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jian HuangDepartment of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital and Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.ORCID https://orcid.org/0000-0002-0363-2412
Dongcun WangDepartment of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital and Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.
Jiping DaDepartment of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital and Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, China.

Funding

Supported by Sanming Project of Medicine in Shenzhen SZSM20181207
6 · The paper itself

Abstract

backgroundThe role of retrospective analysis has been evolved greatly in cancer research. We undertook this meta-analysis to evaluate the diagnostic value of Neural networks (NNs) in Fine needle aspiration cytological (FNAC) image of cancer.

methodsWe systematically retrieved 396 literatures on cytodiagnosis of NNs from Cochrane, PubMed, and EMBASE. After screening, only six studies were included in meta-analysis finally. Data was comprehensively analyzed by RevMan and meta-Disc software.

resultsA total of 1165 cases were extracted from six articles. Among them, 593 cases were in the abnormal/positive group and 572 cases in the normal/negative group. The pooled estimates for the NNs cytology were Area under ROC curve (AUC): 0.99, Sensitivity: 0.85 (95% CI:0.82-0.88), Specificity: 0.96 (95% CI:0.94-0.97), Positive Likelihood Ratio (LR):18.43 (95% CI:6.83-49.74), Negative Likelihood Ratio (LR): 0.06 (95% CI:0.001-0.58), and Diagnostic odds ratio (DOR): 343.21 (34.41-3422.77).

conclusionsThis meta-analysis confirms that NNs Automated Classification algorithm can facilitate to some extent the FNCA diagnosis of cancer.

Indexed as

Deep LearningAlgorithmsBiopsy, Fine-NeedleHumansNeoplasmsRetrospective StudiesSensitivity and SpecificityFNCAmeta-analysisneural networks

Identifiers

PMID32530573
PMCPMC7687103

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.