Evidence map›Paper›PMID 32530494›Full record

ArticleJournal of medical virology2020

Clinical outcomes of 402 patients with COVID-2019 from a single center in Wuhan, China.

Yingjie Wu, Wei Guo, Huan Liu, Bei Qi, Ke Liang, Haibo Xu, Zhiyong Peng, Shu-Yuan Xiao

Abstract read
In one paragraph

Article in Journal of medical virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. COVID-19 and inflammatory bowel disease: A pathophysiological assessment.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. COVID-19: Molecular and Cellular Response.Frontiers in cellular and infection microbiology · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingjie WuDepartment of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID 0000-0002-8307-2258
Wei GuoDepartment of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Huan LiuDepartment of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Bei QiDepartment of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Ke LiangDepartment of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China.
Haibo XuDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
Zhiyong PengDepartment of Critical Care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China.
Shu-Yuan XiaoDepartment of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China.ORCID 0000-0003-0484-932X

Funding

Fundamental Research Funds for the Central Universities 2042020kf1017
6 · The paper itself

Abstract

The outbreak of SARS-CoV-2 has become a pandemic with significant mortality. Published studies described clinical characteristics of the disease contain small cohorts from individual centers or larger series consisting of mixed series from multiple different hospitals. We report here analyses of mortality and disease severity among 402 patients from a single hospital. The cohort includes 297 patients with confirmed and 105 with clinical diagnosis. The latter group consists of cases with inconclusive nucleic acid test but meeting the criteria for clinical diagnosis. Data are compared between sexes and among different age groups. The overall case fatality is 5.2%. However, age at 70 years or older is associated with a significantly higher mortality (17.8%) and higher rate of severe and critical illness (57.5%). Case fatality is 8% in patients 50 years of age or older, and 1.2% in those younger than 50 years. In addition, case fatality is 7.6% in male patients, as opposed to 2.9% in females, demonstrating a clear sex difference.

Indexed as

AdolescentAdultAgedAge FactorsChildChild, PreschoolChinaCOVID-19FemaleHumansMaleMiddle AgedSeverity of Illness IndexSex FactorsYoung AdultcoronavirusCOVID-19diagnosisepidemiologyfatalitymortalitySARS-CoV-2

Identifiers

PMID32530494
PMCPMC7307018

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.