Evidence map›Paper›PMID 32529747›Full record

ArticleAdvanced healthcare materials2020

Tumor Microenvironment Targeting Nano-Bio Emulsion for Synergistic Combinational X-Ray PDT with Oncolytic Bacteria Therapy.

Wooram Park, Soojeong Cho, Dongkyu Kang, Jun-Hyeok Han, Jung-Hoon Park, Byeongdu Lee, Joonseok Lee, Dong-Hyun Kim

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Metabolic Gadolinium Labeling ofBiomaterials research · 2026
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  10. Bacterial-Mediated Tumor Therapy: Old Treatment in a New Context.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Wooram ParkDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Soojeong ChoDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.
Dongkyu KangMolecular Recognition Research Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Jun-Hyeok HanDepartment of Biomedical-Chemical Engineering, The Catholic University of Korea, 43 Jibong-ro, Bucheon-si, Gyeonggi, 14662, Republic of Korea.
Jung-Hoon ParkBiomedical Engineering Research Center, Asan Institute for Life Sciences, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.
Byeongdu LeeX-Ray Science Division, Argonne National Laboratory, Argonne, IL, 60439, USA.
Joonseok LeeMolecular Recognition Research Center, Korea Institute of Science and Technology (KIST), Seoul, 02792, Republic of Korea.
Dong-Hyun KimDepartment of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.ORCID 0000-0001-6815-3319
Northwestern University · USArgonne National Laboratory · USAsan Medical Center · KRHanyang University · KRKorea Institute of Science and Technology · KRKorea University · KR

Funding

Catheter-Directed Image-Guided Delivery of Cytostatic and Cytotoxic Combination Therapy to Liver TumorsR01CA218659 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2022
$1.9M
Image-Guided Transcatheter Delivery of Natural Killer Cell Therapy Augmented with IFN-Gamma Eluting MicrospheresR01EB026207 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DONG-HYUN · 2018 to 2021
$1.4M
NCI NIH HHS R01 CA218659NIBIB NIH HHS R01 EB026207
6 · The paper itself

Abstract

Various cancer therapies have been developed, but tumor recurrence with incomplete tumor killing and remaining tumor cells/tissues is frequent in monotherapies. Herein, a nano-bio therapeutic emulsion formulated with multifunctional nanoscintillators and anaerobic Clostridium novyi-NT spores for synergistic image-guided combinational cancer therapy is reported. MRI visible nanoscintillators (NSs) are synthesized with a NaGdF

Indexed as

PhotochemotherapyTumor MicroenvironmentClostridiumEmulsionsX-RaysEmulsionsbacteriolytic therapynano-bio emulsionsscintillating nanoparticlestumor microenvironmentsX-ray photodynamic therapy (PDT)

Identifiers

PMID32529747
PMCPMC7523430
OpenAlexW3034841467

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.