Evidence map›Paper›PMID 32529516›Full record

ArticleJournal of neurovirology2020

Miller Fisher syndrome diagnosis and treatment in a patient with SARS-CoV-2.

Paolo Manganotti, Valentina Pesavento, Alex Buoite Stella, Lucia Bonzi, Elena Campagnolo, Giulia Bellavita, Bruno Fabris, Roberto Luzzati

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Journal of neurovirology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 12 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 12 syntheses or guidelines pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  3. COVID-19 associated cranial nerve neuropathy: A systematic review.Bosnian journal of basic medical sciences · 2022
    Pooled it
  4. Guillain Barre Syndrome as a Complication of COVID-19: A Systematic Review.The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2022
    Pooled it
  5. Pooled it
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  7. Miller Fisher syndrome associated with COVID-19: an up-to-date systematic review.Environmental science and pollution research international · 2021
    Pooled it
  8. Pooled it
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  11. Neurological manifestations of COVID-19: a systematic review and meta-analysis of proportions.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Pooled it
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  18. Cognitive deficit in post-acute COVID-19: an opportunity for EEG evaluation?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Paolo ManganottiClinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy. pmanganotti@units.it.
Valentina PesaventoRehabilitation Unit, Cattinara University Hospital ASUGI, Via Giuseppe Lorenzo Gatteri, 25/1, 34125, Trieste, Italy.
Alex Buoite StellaClinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
Lucia BonziRehabilitation Unit, Cattinara University Hospital ASUGI, Via Giuseppe Lorenzo Gatteri, 25/1, 34125, Trieste, Italy.
Elena CampagnoloEndocrinology Unit, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
Giulia BellavitaClinical Unit of Neurology, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
Bruno FabrisEndocrinology Unit, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
Roberto LuzzatiInfectious Diseases Department, Department of Medicine, Surgery and Health Sciences, Cattinara University Hospital ASUGI, University of Trieste, Strada di Fiume, 447, 34149, Trieste, Italy.
Ospedale di Cattinara · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes the clinical characteristics of a 50-year-old woman that developed SARS-CoV-2 pneumonia and was admitted at the COVID-19 dedicated unit where she developed neurological symptoms 10 days after admission. After neurological examination, including a panel of blood cerebrospinal fluid biomarkers, a diagnosis of Miller Fisher syndrome (MFS) was hypothesized and intravenous immunoglobulin therapy (IVIG) was initiated. Fourteen days after the start of IVIG treatment, the patient has been discharged at home with the resolution of respiratory symptoms and only minor hyporeflexia at the lower limbs, without any side effect.

Indexed as

BetacoronavirusCoronavirus InfectionsCOVID-19FemaleHumansImmunoglobulins, IntravenousMiddle AgedMiller Fisher SyndromePandemicsPneumonia, ViralSARS-CoV-2Immunoglobulins, IntravenousCOVID-19Cranial polyneuritisImmunoglobulinsMiller Fisher syndrome

Identifiers

PMID32529516
PMCPMC7288617
OpenAlexW3035264571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.