Evidence map›Paper›PMID 32529506›Full record

Trial reportEuropean journal of applied physiology2020

Left atrial mechanics and aortic stiffness following high intensity interval training: a randomised controlled study.

Navazh Jalaludeen, Samuel J Bull, Katrina A Taylor, Jonathan D Wiles, Damian A Coleman, Lucinda Howland, Omar Mukhtar, Joseph Cheriyan, Ian B Wilkinson, Rajan Sharma and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Navazh JalaludeenCambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Samuel J BullSchool of Human and Life Sciences, Canterbury Christ Church University, Kent, CT1 1QU, UK.
Katrina A TaylorSchool of Human and Life Sciences, Canterbury Christ Church University, Kent, CT1 1QU, UK.
Jonathan D WilesSchool of Human and Life Sciences, Canterbury Christ Church University, Kent, CT1 1QU, UK.
Damian A ColemanSchool of Human and Life Sciences, Canterbury Christ Church University, Kent, CT1 1QU, UK.
Lucinda HowlandSchool of Human and Life Sciences, Canterbury Christ Church University, Kent, CT1 1QU, UK.
Omar MukhtarCambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Joseph CheriyanCambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Ian B WilkinsonCambridge Clinical Trials Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Rajan SharmaDepartment of Cardiology, St George's Healthcare NHS Trust, Blackshaw Road, Tooting, London, UK.
Jamie M O'DriscollSchool of Human and Life Sciences, Canterbury Christ Church University, Kent, CT1 1QU, UK. jamie.odriscoll@canterbury.ac.uk.
Canterbury Christ Church University · GBCambridge University Hospitals NHS Foundation Trust · GBSouth West London and St George's Mental Health NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHigh intensity interval training (HIIT) has been shown to improve important health parameters, including aerobic capacity, blood pressure, cardiac autonomic modulation and left ventricular (LV) mechanics. However, adaptations in left atrial (LA) mechanics and aortic stiffness remain unclear.

methodsForty-one physically inactive males and females were recruited. Participants were randomised to either a 4-week HIIT intervention (n = 21) or 4-week control period (n = 20). The HIIT protocol consisted of 3 × 30-s maximal cycle ergometer sprints with a resistance of 7.5% body weight, interspersed with 2-min of active unloaded recovery, three times per week. Speckle tracking imaging of the LA and M-Mode tracing of the aorta was performed pre and post HIIT and control period.

resultsFollowing HIIT, there was significant improvement in LA mechanics, including LA reservoir (13.9 ± 13.4%, p = 0.033), LA conduit (8.9 ± 11.2%, p = 0.023) and LA contractile (5 ± 4.5%, p = 0.044) mechanics compared to the control condition. In addition, aortic distensibility (2.1 ± 2.7 cm

conclusionA short-term programme of HIIT was associated with a significant improvement in LA mechanics and aortic stiffness. These adaptations may have important health implications and contribute to the improved LV diastolic and systolic mechanics, aerobic capacity and blood pressure previously documented following HIIT.

Indexed as

Atrial Function, LeftVascular StiffnessAdultAortaFemaleHeart AtriaHigh-Intensity Interval TrainingHumansMaleAortic stiffnessHIITLeft atrial mechanics

Identifiers

PMID32529506
OpenAlexW3035063923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.