ReviewHead and neck pathology2021
Orbit Solitary Fibrous Tumor: A Proposed Risk Prediction Model Based on a Case Series and Comprehensive Literature Review.
Review in Head and neck pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Solitary fibrous tumor of the oral cavity: a systematic review of the literature and a new clinicopathologic case report.Frontiers in oral health · 2026Pooled it
- Article
- Solitary fibrous tumor: an updated review.Journal of pathology and translational medicine · 2026Article
- Solitary Fibrous Tumor of the Forehead.Indian dermatology online journal · 2025Article
- The Solitary Fibrous Tumor, the Chameleon of the Head and Neck Region-Clinical, Epidemiological, and Histopathological Aspects.Diagnostics (Basel, Switzerland) · 2025Article
- Clinicopathological and genetic analysis of orbital solitary fibrous tumors.BMC ophthalmology · 2025Article
- Article
- Solitary fibrous tumors: radiologic features with clinical and histopathologic correlation.Frontiers in oncology · 2025Article
- Solitary Fibrous Tumor of the Mandible.Head and neck pathology · 2024Article
- MR Imaging Characteristics of Solitary Fibrous Tumors of the Orbit : Case Series of 18 Patients.Clinical neuroradiology · 2024Article
- Article
- Prevalence ofCurrent issues in molecular biology · 2024Article
- Presentation of orbital solitary fibrous tumours.Eye (London, England) · 2023Article
- Extra-meningeal solitary fibrous tumor: an evolving entity with chameleonic morphological diversity, a hallmark molecular alteration and unresolved issues in risk stratification assessment.Histology and histopathology · 2023Review
- Bilobed flap reconstruction after en-bloc removal of solitary fibrous tumor of the lacrimal sac.American journal of ophthalmology case reports · 2023Article
- A review of solitary fibrous tumours of the orbit and ocular adnexa.Eye (London, England) · 2023Review
- Prognostic analysis of extrameningeal solitary fibrous tumor using the modified Demicco model: a clinicopathologic study of 111 Chinese cases.Frontiers in oncology · 2023Article
- Preoperative Endovascular Embolization of Orbital Solitary Fibrous Tumor With 500-700 Micron Tris-Acryl Gelatin Microspheres.Turkish journal of ophthalmology · 2022Article
- Giant cell-rich solitary fibrous tumour of the lacrimal gland with prominent angiomatoid cystic changes and an underlying NAB2ex3-STAT6ex18 fusion.BMJ case reports · 2022Article
- Factors for postoperative recurrence of orbital solitary fibrous tumor: an analysis of long-term clinical follow-up results from a Chinese tertiary hospital.BMC ophthalmology · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solitary fibrous tumors (SFTs) of the orbit are rare. In order to further characterize the clinical and pathologic features of solitary fibrous tumor arising at this anatomic site, 12 cases of orbital SFTs were analyzed in conjunction with a review of 263 cases reported from the English literature in order to develop a risk prediction model. SFTs of the orbit were equally distributed between males (n = 5) and females (n = 7) with a mean patient age of 46.8 years (median 44.5 years; range 18-76 years) at initial diagnosis. The patients typically presented with swelling or mass around the orbit, with proptosis (n = 10), ptosis (n = 5), and visual changes (n = 6). Tumors were orbital (n = 10) or upper eyelid (n = 2). Mean tumor size was 2.5 cm (median 2.6 cm). Microscopically, the tumors were characterized by cytologically bland spindle cells with patternless growth, hypocellular and hypercellular areas, variable amounts of collagen, and ectatic, branching blood vessels. By immunohistochemistry, all cases had a strong nuclear STAT6 expression. All patients were initially managed with excision or biopsy, three with presurgical embolization. The two patients with biopsy only had persistent disease (mean 37.2 months), but a third patient developed distant bone metastasis at 86.9 months. Overall mean follow-up was 73.1 months: 9 patients are alive or dead without disease (mean 77.9 months), two patients with persistent disease, and one patient with metastatic disease at last follow-up (102 months). Incorporating cases sufficiently reported in the literature, a risk prediction model based on age > 45 years, tumor size > 3 cm, tumor necrosis, mitoses of > 4/2 mm
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