Evidence map›Paper›PMID 32529305›Full record

ReviewCurrent pain and headache reports2020

A Comprehensive Review of the Celiac Plexus Block for the Management of Chronic Abdominal Pain.

Ivan Urits, Mark R Jones, Vwaire Orhurhu, Jacquelin Peck, Devin Corrigan, Ashley Hubble, Megan Andrews, Ruby Feng, Laxmaiah Manchikanti, Alan D Kaye and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current pain and headache reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Phenol Neurolysis in Pain and Palliative Medicine.Pain practice : the official journal of World Institute of Pain · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Ivan UritsBeth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA. ivanurits@gmail.com.
Mark R JonesBeth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Vwaire OrhurhuBeth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Jacquelin PeckDepartment of Anesthesiology, Mt. Sinai Medical Center of Florida, Miami Beach, FL, USA.
Devin CorriganCreighton University School of Medicine-Phoenix Regional Campus, Phoenix, AZ, USA.
Ashley HubbleCreighton University School of Medicine-Phoenix Regional Campus, Phoenix, AZ, USA.
Megan AndrewsCreighton University School of Medicine-Phoenix Regional Campus, Phoenix, AZ, USA.
Ruby FengBeth Israel Deaconess Medical Center, Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.
Laxmaiah ManchikantiPain Management Centers of America, Paducah, KY, USA.
Alan D KayeDepartment of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, Louisiana State University School of Medicine, Shreveport, LA, USA.
Rachel J KayeDepartment of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, Louisiana State University School of Medicine, Shreveport, LA, USA.
Omar ViswanathDepartment of Anesthesiology and Pharmacology, Toxicology, and Neurosciences, Louisiana State University School of Medicine, Shreveport, LA, USA.
Harvard University · USPhoenix (United States) · USLouisiana State University in Shreveport · USBeth Israel Deaconess Medical Center · USCreighton University · USMount Sinai Medical Center · USPain Management Centers Of America · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewChronic abdominal pain (CAP) is a significant health problem that can dramatically affect quality of life and survival. Pancreatic cancer is recognized as one of the most painful malignancies with 70-80% suffering from substantial pain, often unresponsive to typical medical management. Celiac plexus neurolysis and celiac plexus block (CPB) can be performed to mitigate pain through direct destruction or blockade of visceral afferent nerves. The objective of this manuscript is to provide a comprehensive review of the CPB as it pertains to CAP with a focus on the associated anatomy, indications, techniques, neurolysis/blocking agents, and complications observed in patients who undergo CPB for the treatment of CAP. RECENT

findingsThe CAP is difficult to manage due to lack of precision in diagnosis and limited evidence from available treatments. CAP can arise from both benign and malignant causes. Treatment options include pharmacologic, interventional, and biopsychosocial treatments. Opioid therapy is typically utilized for the treatment of CAP; however, opioid therapy is associated with multiple complications. CPB has successfully been used to treat a variety of conditions resulting in CAP. The majority of the literature specifically related to CPB is surrounding chronic pain associated with pancreatic cancer. The literature shows emerging evidence in managing CAP with CPB, specifically in pancreatic cancer. This review provides multiple aspects of CAP and CPB, including anatomy, medical necessity, indications, technical considerations, available evidence, and finally complications related to the management.

Indexed as

Celiac PlexusAbdominal PainChronic PainEthanolGlucocorticoidsHumansNerve BlockPancreatic NeoplasmsPancreatitis, ChronicPhenolTriamcinoloneVisceral PainEthanolGlucocorticoidsPhenolTriamcinoloneCeliac plexus blockChronic abdominal painNeurolytic agentsNeurolytic blocksPancreatic cancer

Identifiers

PMID32529305
OpenAlexW3035070646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.