Evidence map›Paper›PMID 32529194›Full record

ArticleDermatology case reports2019

Thalidomide, A Rational Agent for Treatment of Multicentric Reticulohistiocytosis.

Daniel J Zinn, Olive Eckstein, Mary L Olsen, Carl E Allen, Kenneth L McClain

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Dermatology case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Daniel J ZinnDepartment of Pediatrics, Lehigh Valley Reilley Children's Hospital, Allentown, Pennsylvania, USA.
Olive EcksteinTexas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas, USA.
Mary L OlsenBaptist Physicians Network, Rheumatology Center, Beaumont, Texas, USA.
Carl E AllenTexas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas, USA.
Kenneth L McClainTexas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas, USA.
Baylor College of Medicine · USChildren's Cancer Center · USLehigh Valley Hospital-Pocono · US

Funding

PEDIATRIC ONCOLOGY CLINICAL RESEARCH TRAINING PROGRAMK12CA090433 · NCI · BAYLOR COLLEGE OF MEDICINE · PI CARL E ALLEN, Donald W. Parsons · 2002 to 2026
$18.5M
Redefining Langerhans Cell Histiocytosis as a Myeloid Dysplasia and Identifying BR01CA154489 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ALLEN, CARL E · 2011 to 2015
$1.6M
NCI NIH HHS K12 CA090433NCI NIH HHS R01 CA154489
6 · The paper itself

Abstract

A patient with Multifocal Reticulohistiocytosis (MRH) of skin and joints failed treatment with etanercept, methotrexate, hydroxychloroquine, prednisone, bisphosphonates and hydroxyzine. Long term treatment with thalidomide led to marked improvement in joint and cutaneous manifestations.

Indexed as

Histiocytic disordersMulticentric reticulohistiocytosisReticulohistiocytosisThalidomide

Identifiers

PMID32529194
PMCPMC7289025
OpenAlexW2952912492

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.