Evidence map›Paper›PMID 32528941›Full record

ReviewFrontiers in bioengineering and biotechnology2020

Near Infrared Light Triggered Photo/Immuno-Therapy Toward Cancers.

Xiaoxue Xu, Hongxu Lu, Ruda Lee

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 81 citations in OpenAlex.

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  15. One stone, many birds: Recent advances in functional nanogels for cancer nanotheranostics.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022
    Review
  16. Review
  17. Multifunctional inorganic nanomaterials for cancer photoimmunotherapy.Cancer communications (London, England) · 2022
    Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Xiaoxue XuInstitute for Biomedical Materials and Devices, Faculty of Science, University of Technology, Sydney, NSW, Australia.
Hongxu LuInstitute for Biomedical Materials and Devices, Faculty of Science, University of Technology, Sydney, NSW, Australia.
Ruda LeeInternational Research Organization for Advanced Science and Technology, Kumamoto University, Kumamoto, Japan.
University of Technology Sydney · AUKumamoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomaterials-based phototherapies, mainly including photothermal therapy (PTT), photodynamic therapy (PDT) and photoimmunotherapy (PIT), present high efficacy, minimal invasion and negligible adverse effects in cancer treatment. The integrated phototherapeutic modalities can enhance the efficiency of cancer immunotherapy for clinical application transformation. The near-infrared (NIR) light source enables phototherapies with the high penetration depth in the biological tissues, less toxic to normal cells and tissues and a low dose of light irradiation. Mediated via the novel NIR-responsive nanomaterials, PTT and PDT are able to provoke cancer cells apoptosis from the generated heat and reactive oxygen species, respectively. The released cancer-specific antigens and membrane damage danger signals from the damaged cancer cells trigger immune responses, which would enhance the antitumor efficacy via a variety of immunotherapy. This review summarized the recent advances in NIR-triggered photo-/immune-therapeutic modalities and their synergistic mechanisms and applications toward cancers. Furthermore, the challenges, potential solutions and future directions of NIR-triggered photo-/immunotherapy were briefly discussed.

Indexed as

cancercancer phototherapynear infrared lightphotodynamic therapyphoto/immune-therapyphotothermal therapy (PTT)

Identifiers

PMID32528941
PMCPMC7264102
OpenAlexW3029354292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.