Evidence map›Paper›PMID 32528825›Full record

ReviewActa pharmaceutica Sinica. B2020

Natural products, PGC-1

Ipek Suntar, Antoni Sureda, Tarun Belwal, Ana Sanches Silva, Rosa Anna Vacca, Devesh Tewari, Eduardo Sobarzo-Sánchez, Seyed Fazel Nabavi, Samira Shirooie, Ahmad Reza Dehpour and 6 more

Open access · diamondAbstract readReview
In one paragraph

Review in Acta pharmaceutica Sinica. B, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. NMN Can Restore Ovarian Reserve in Aged Mice by Upregulating NADReproductive sciences (Thousand Oaks, Calif.) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 12 institutions in 7 countries.

Ipek SuntarDepartment of Pharmacognosy, Faculty of Pharmacy, Gazi University, Etiler, Ankara 06330, Turkey.
Antoni SuredaResearch Group in Community Nutrition and Oxidative Stress, Health Research Institute of the Balearic Islands (IdISBa), and CIBEROBN (Physiopathology of Obesity and Nutrition), University of Balearic Islands, Palma, Balearic Islands E-07122, Spain.
Tarun BelwalG. B. Pant National Institute of Himalayan Environment and Sustainable Development, Kosi-Katarmal, Almora, Uttarakhand 263643, India.
Ana Sanches SilvaNational Institute for Agricultural and Veterinary Research (INIAV), Vairão, Vila do Conde, Portugal.
Rosa Anna VaccaInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies, National Council of Research, Bari 70126, Italy.
Devesh TewariDepartment of Pharmacognosy, School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411, India.
Eduardo Sobarzo-SánchezLaboratory of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela 15782, Spain.
Seyed Fazel NabaviApplied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran 5613156491, Iran.
Samira ShirooiePharmaceutical Sciences Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah 6715847141, Iran.
Ahmad Reza DehpourDepartment of Pharmacology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran 1416753955, Iran.
Suowen XuThe First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230001, China.
Bahman YousefiMolecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz 516615731, Iran.
Maryam MajidiniaSolid Tumor Research Center, Urmia University of Medical Sciences, Urmia 571478334, Iran.
Maria DagliaDepartment of Pharmacy, University of Naples Federico II, Naples 80138, Italy.
Giuseppe D'AntonaDepartment of Public Health, Experimental and Forensic Medicine and CRIAMS-Sport Medicine Centre, University of Pavia, Pavia 27100, Italy.
Seyed Mohammad NabaviApplied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran 5613156491, Iran.
Baqiyatallah University of Medical Sciences · IRJiangsu University · CNUniversity of Science and Technology of China · CNCentro de Investigación Biomédica en Red · ESGazi University · TRG.B. Pant Institute of Himalayan Environment and Development · INInstitute of Biomembranes, Bioenergetics and Molecular Biotechnologies · ITKermanshah University of Medical Sciences · IRLovely Professional University · INTabriz University of Medical Sciences · IRUniversidade de Santiago de Compostela · ESUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxisome proliferator-activated receptor

Indexed as

AAV, adeno-associated virusAMP, adenosine monophosphateAMPK, 5′ adenosine monophosphate-activated protein kinaseASO, antisense oligonucleotidesATF2, activating transcription factor 2ATP, adenosine triphosphateBMD, Becker muscular dystrophycGMP, cyclic guanosine monophosphateCnA, calcineurin aCOPD, chronic obstructive pulmonary diseaseCREB, cyclic AMP response element-binding proteinDAGC, dystrophin-associated glycoprotein complexDGC, dystrophin–glycoprotein complexDMD, Duchenne muscular dystrophyDRP1, dynamin-related protein 1DS, Down syndromeECM, extracellular matrixEGCG, epigallocatechin-3-gallateERRα, estrogen-related receptor alphaFDA, U. S. Food and Drug AdministrationFGF, fibroblast growth factorFOXO1, forkhead box class-O1GABP, GA-binding proteinGPX, glutathione peroxidaseGSK3b, glycogen synthase kinase 3bHCT, hydrochlorothiazideHDAC, histone deacetylaseHIF-1α, hypoxia-inducible factorsIL, interleukiniPSCs, induced pluripotent stem cellsLDH, lactate dehydrogenaseMCP-1, monocyte chemoattractant protein-1MD, muscular dystrophyMEF2, myocyte enhancer factor 2Mitochondrial oxidative phosphorylationMSCs, mesenchymal stem cellsMuscular dystrophyMyoD, myogenic differentiationNADPH, nicotinamide adenine dinucleotide phosphateNatural productNF-κB, nuclear factor kappa-light-chain-enhancer of activated B cellsNMJ, neuromuscular junctionsNO, nitric oxideNOS, NO synthasep38 MAPK, p38 mitogen-activated protein kinasePDGF, platelet derived growth factorPeroxisome proliferator-activated receptor γ coactivator 1αPGC-1, peroxisome proliferator-activated receptor γ coactivator 1PPARγ activationPPARγ, peroxisome proliferator-activated receptor γReactive oxygen speciesROS, reactive oxygen speciesSIRT1, silent mating type information regulation 2 homolog 1SOD, superoxide dismutaseSPP1, secreted phosphoprotein 1TNF-α, tumor necrosis factor-αUCP, uncoupling proteinVEGF, vascular endothelial growth factor

Identifiers

PMID32528825
PMCPMC7276681
OpenAlexW3000507528

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.