Evidence map›Paper›PMID 32528268›Full record

ArticleFrontiers in computational neuroscience2020

Emergent Spaces for Coupled Oscillators.

Thomas N Thiem, Mahdi Kooshkbaghi, Tom Bertalan, Carlo R Laing, Ioannis G Kevrekidis

Abstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas N ThiemDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ, United States.
Mahdi KooshkbaghiProgram in Applied and Computational Mathematics, Princeton University, Princeton, NJ, United States.
Tom BertalanDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States.
Carlo R LaingSchool of Natural and Computational Sciences, Massey University, Auckland, New Zealand.
Ioannis G KevrekidisChemical and Biomolecular Engineering and Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, United States.

Funding

Multiscale Modeling of the Mammalian Circadian Clock: The Role of GABA SignalingU01EB021956 · NIBIB · UNIVERSITY OF MASSACHUSETTS AMHERST · PI HENSON, MICHAEL, HERZOG, ERIK · 2016 to 2019
$1.8M
NIBIB NIH HHS U01 EB021956
6 · The paper itself

Abstract

Systems of coupled dynamical units (e.g., oscillators or neurons) are known to exhibit complex, emergent behaviors that may be simplified through coarse-graining: a process in which one discovers coarse variables and derives equations for their evolution. Such coarse-graining procedures often require extensive experience and/or a deep understanding of the system dynamics. In this paper we present a systematic, data-driven approach to discovering "bespoke" coarse variables based on manifold learning algorithms. We illustrate this methodology with the classic Kuramoto phase oscillator model, and demonstrate how our manifold learning technique can successfully identify a coarse variable that is one-to-one with the established Kuramoto order parameter. We then introduce an extension of our coarse-graining methodology which enables us to learn evolution equations for the discovered coarse variables via an artificial neural network architecture templated on numerical time integrators (initial value solvers). This approach allows us to learn accurate approximations of time derivatives of state variables from sparse flow data, and hence discover useful approximate differential equation descriptions of their dynamic behavior. We demonstrate this capability by learning ODEs that agree with the known analytical expression for the Kuramoto order parameter dynamics at the continuum limit. We then show how this approach can also be used to learn the dynamics of coarse variables discovered through our manifold learning methodology. In both of these examples, we compare the results of our neural network based method to typical finite differences complemented with geometric harmonics. Finally, we present a series of computational examples illustrating how a variation of our manifold learning methodology can be used to discover sets of "effective" parameters, reduced parameter combinations, for multi-parameter models with complex coupling. We conclude with a discussion of possible extensions of this approach, including the possibility of obtaining data-driven effective partial differential equations for coarse-grained neuronal network behavior, as illustrated by the synchronization dynamics of Hodgkin-Huxley type neurons with a Chung-Lu network. Thus, we build an integrated suite of tools for obtaining data-driven coarse variables, data-driven effective parameters, and data-driven coarse-grained equations from detailed observations of networks of oscillators.

Indexed as

complex networkscoupled systemsdiffusion mapsgeometric harmonicsKuramoto oscillatorsmanifold learningneural networks

Identifiers

PMID32528268
PMCPMC7247828

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.