Evidence map›Paper›PMID 32528241›Full record

ReviewFrontiers in neuroscience2020

Potential Preventive Strategies for Amyotrophic Lateral Sclerosis.

B Kuraszkiewicz, H Goszczyńska, T Podsiadły-Marczykowska, M Piotrkiewicz, P Andersen, M Gromicho, J Grosskreutz, M Kuźma-Kozakiewicz, S Petri, B Stubbendorf and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
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  6. Article
  7. Melatonin in Wine and Beer: Beneficial Effects.Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 5 countries.

B KuraszkiewiczDepartment of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.
H GoszczyńskaDepartment of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.
T Podsiadły-MarczykowskaDepartment of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.
M PiotrkiewiczDepartment of Methods of Brain Imaging and Functional Research of Nervous System, Nalecz Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, Warsaw, Poland.
P AndersenDepartment of Clinical Sciences, Umeå University, Umeå, Sweden.
M GromichoInstitute of Physiology, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
J GrosskreutzDepartment of Neurology, University Hospital Jena, Jena, Germany.
M Kuźma-KozakiewiczDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
S PetriClinic for Neurology, Hannover Medical School, Hanover, Germany.
B StubbendorfDepartment of Neurology, University Hospital Jena, Jena, Germany.
K SzackaDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
H UysalAkdeniz University Faculty of Medicine, Antalya, Turkey.
M de CarvalhoInstitute of Physiology, Faculty of Medicine, University of Lisbon, Lisbon, Portugal.
Institute of Biocybernetics and Biomedical Engineering · PLJena University Hospital · DEMedical University of Warsaw · PLUniversity of Lisbon · PTAkdeniz University · TRMedizinische Hochschule Hannover · DEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.

Indexed as

agingamyotrophic lateral sclerosisdietary habitsexercisegut microbiomepsychological stress

Identifiers

PMID32528241
PMCPMC7264408
OpenAlexW3029435842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.