Evidence map›Paper›PMID 32528233›Full record

ReviewJournal of inflammation (London, England)2020

SARS-CoV-2 COVID-19 susceptibility and lung inflammatory storm by smoking and vaping.

Gagandeep Kaur, Giuseppe Lungarella, Irfan Rahman

Open access · goldAbstract readReview
In one paragraph

Review in Journal of inflammation (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 2 pooled it
2.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. TNFα-mediated subcellular heterogeneity of succinate dehydrogenase activity in human airway smooth muscle cells.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  5. Article
  6. Article
  7. E-cigarette use-associated lung injury (EVALI).Pneumologie (Stuttgart, Germany) · 2024
    Article
  8. Development of Chatbot-Assisted Smoking Cessation Telehealth Intervention: A Case Report.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Gagandeep KaurDepartment of Environmental Medicine, University of Rochester Medical Center, Box 850, 601 Elmwood Avenue, Rochester, NY 14642 USA.
Giuseppe LungarellaDepartment of Molecular and Developmental Medicine, University of Siena, Siena, Italy.
Irfan RahmanDepartment of Environmental Medicine, University of Rochester Medical Center, Box 850, 601 Elmwood Avenue, Rochester, NY 14642 USA.
University of Rochester Medical Center · USUniversity of Siena · IT

Funding

Inflammatory and Dysregulated Repair Responses to Inhaled NicotineR01HL135613 · NHLBI · UNIVERSITY OF ROCHESTER · PI RAHMAN, IRFAN · 2017 to 2021
$2.7M
Molecular clock dysfunction in lung cellular senescence by environmental tobacco smokeR01ES029177 · NIEHS · UNIVERSITY OF ROCHESTER · PI RAHMAN, IRFAN · 2019 to 2023
$1.7M
NHLBI NIH HHS R01 HL135613NIEHS NIH HHS R01 ES029177
6 · The paper itself

Abstract

The current pandemic of COVID-19 has caused severe morbidity and mortality across the globe. People with a smoking history have severe disease outcomes by COVID-19 infection. Epidemiological studies show that old age and pre-existing disease conditions (hypertension and diabetes) result in severe disease outcome and mortality amongst COVID-19 patients. Evidences suggest that the S1 domain of the SARS-CoV-2 (causative agent of COVID-19) membrane spike has a high affinity towards the

Indexed as

ACE2COVID-19E-cigarettesInflammationSARS-CoV2SmokingVaping

Identifiers

PMID32528233
PMCPMC7284674
OpenAlexW3033164116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.