Evidence map›Paper›PMID 32528189›Full record

ReviewNature reviews. Nephrology2020

Plant-based diets to manage the risks and complications of chronic kidney disease.

Juan J Carrero, Ailema González-Ortiz, Carla M Avesani, Stephan J L Bakker, Vincenzo Bellizzi, Philippe Chauveau, Catherine M Clase, Adamasco Cupisti, Angeles Espinosa-Cuevas, Pablo Molina and 5 more

Registry-linked trialOpen access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07494266 (Säkerheten av en hälsosam växtbaserad Kost Med högre kaliuminnerhåll, jämfört Med en hälsosam växtbaserad Kost Med begränsat kaliuminnehåll Hos Patienter Med Kronisk Njursjukdom), which is not on this map. Cited by 167 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed, 5 pooled it
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07494266 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Säkerheten av en hälsosam växtbaserad Kost Med högre kaliuminnerhåll, jämfört Med en hälsosam växtbaserad Kost Med begränsat kaliuminnehåll Hos Patienter Med Kronisk Njursjukdom: En Pilotstudie

TypeinterventionalSponsorKarolinska InstitutetRan2026 to 2030Enrolled30ConditionsHyperkalemia, Chronic Kidney Disease (Stages 4 and 5)ArmsHealthy plant-based diet (healthy-PBD), Potassium-restricted plant-based diet
3 · Its place in the literature

Who cites it

167 citing papers in PubMed, 5 syntheses or guidelines pooled it, 295 citations in OpenAlex.

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107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 8 countries.

Juan J CarreroMedical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. juan.jesus.carrero@ki.se.
Ailema González-OrtizMedical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-8891-9892
Carla M AvesaniClinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-4458-8358
Stephan J L BakkerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0003-3356-6791
Vincenzo BellizziNephrology Unit, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy.ORCID http://orcid.org/0000-0001-9374-0152
Philippe ChauveauService de Néphrologie Transplantation Dialyse, Centre Hospitalier Universitaire de Bordeaux et Aurad-Aquitaine, Bordeaux, France.ORCID http://orcid.org/0000-0002-7072-195X
Catherine M ClaseDepartments of Medicine and Health Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.
Adamasco CupistiDepartment of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.ORCID http://orcid.org/0000-0002-8995-936X
Angeles Espinosa-CuevasNephrology and Mineral Metabolism Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador, Zubirán, Mexico.ORCID http://orcid.org/0000-0001-9153-5155
Pablo MolinaDepartment of Nephrology, Hospital Universitari Dr Peset, Universitat de València, València, Spain.
Karine MoreauRenal transplant unit, Pellegrin Hospital, Bordeaux, France.ORCID http://orcid.org/0000-0002-6788-5427
Giorgina B PiccoliDepartment of Clinical and Biological Sciences, University of Torino, Torino, Italy.ORCID http://orcid.org/0000-0002-2632-4009
Adrian PostDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0001-8645-1627
Siren SezerDepartment of Nephrology, Baskent University School of Medicine, Ankara, Turkey.
Denis FouqueDepartment of Nephrology, Université de Lyon, Carmen, Hospital Lyon-Sud, Lyon, France.ORCID http://orcid.org/0000-0002-9707-7199
Karolinska Institutet · SEUniversity Medical Center Groningen · NLBaşkent University · TRCentre Hospitalier du Mans · FRCentre Hospitalier Universitaire de Bordeaux · FRHôpital Pellegrin · FRImpact · CAInstituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán · MXOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITUniversitat de València · ESUniversité Claude Bernard Lyon 1 · FRUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional dietary recommendations for patients with chronic kidney disease (CKD) focus on the quantity of nutrients consumed. Without appropriate dietary counselling, these restrictions can result in a low intake of fruits and vegetables and a lack of diversity in the diet. Plant nutrients and plant-based diets could have beneficial effects in patients with CKD: increased fibre intake shifts the gut microbiota towards reduced production of uraemic toxins; plant fats, particularly olive oil, have anti-atherogenic effects; plant anions might mitigate metabolic acidosis and slow CKD progression; and as plant phosphorus has a lower bioavailability than animal phosphorus, plant-based diets might enable better control of hyperphosphataemia. Current evidence suggests that promoting the adoption of plant-based diets has few risks but potential benefits for the primary prevention of CKD, as well as for delaying progression in patients with CKD G3-5. These diets might also help to manage and prevent some of the symptoms and metabolic complications of CKD. We suggest that restriction of plant foods as a strategy to prevent hyperkalaemia or undernutrition should be individualized to avoid depriving patients with CKD of these potential beneficial effects of plant-based diets. However, research is needed to address knowledge gaps, particularly regarding the relevance and extent of diet-induced hyperkalaemia in patients undergoing dialysis.

Indexed as

Diet, VegetarianAcid-Base EquilibriumDietary Approaches To Stop HypertensionDietary Fats, UnsaturatedDietary FiberDiet, HealthyDiet, MediterraneanDisease ProgressionHumansHyperkalemiaPhosphorus, DietaryPlant Proteins, DietaryPotassium, DietaryRenal DialysisRenal Insufficiency, ChronicDietary Fats, UnsaturatedDietary FiberPhosphorus, DietaryPlant Proteins, DietaryPotassium, Dietary

Identifiers

PMID32528189
OpenAlexW3035275062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.