Evidence map›Paper›PMID 32528181›Full record

ArticleNature2020

A discrete neuronal circuit induces a hibernation-like state in rodents.

Tohru M Takahashi, Genshiro A Sunagawa, Shingo Soya, Manabu Abe, Katsuyasu Sakurai, Kiyomi Ishikawa, Masashi Yanagisawa, Hiroshi Hama, Emi Hasegawa, Atsushi Miyawaki and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed
50.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 254 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Neural Control of Homeothermy, Torpor, and Hibernation.Annual review of neuroscience · 2026
    Review
  10. Pronounced Neuroplasticity in the Primary Visual Cortex of the 13-Lined Ground Squirrel during Hibernation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  11. Neural circuits of torpor.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. A Preoptic Neuronal Population Regulates Energy Expenditure and Balance.bioRxiv : the preprint server for biology · 2026
    Article
  16. Inhibition of daily torpor in mice requires calories, not just feeding: a potential role for GLP-1.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Tohru M TakahashiFaculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Genshiro A SunagawaLaboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan. genshiro.sunagawa@riken.jp.
Shingo SoyaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan.
Manabu AbeDepartment of Cellular Neurobiology, Brain Research Institute, Niigata University, Niigata, Japan.
Katsuyasu SakuraiInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan.
Kiyomi IshikawaLaboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Masashi YanagisawaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan.ORCID http://orcid.org/0000-0002-7358-4022
Hiroshi HamaLaboratory for Cell Function Dynamics, RIKEN Center for Brain Science, Wako, Japan.
Emi HasegawaInternational Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Japan.
Atsushi MiyawakiLaboratory for Cell Function Dynamics, RIKEN Center for Brain Science, Wako, Japan.
Kenji SakimuraDepartment of Animal Model Development, Brain Research Institute, Niigata University, Niigata, Japan.
Masayo TakahashiLaboratory for Retinal Regeneration, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Takeshi SakuraiFaculty of Medicine, University of Tsukuba, Tsukuba, Japan. sakurai.takeshi.gf@u.tsukuba.ac.jp.ORCID http://orcid.org/0000-0003-4474-6253
University of Tsukuba · JPRIKEN Center for Biosystems Dynamics Research · JPNiigata University · JPRIKEN Center for Brain Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hibernating mammals actively lower their body temperature to reduce energy expenditure when facing food scarcity

Indexed as

AnimalsBasal MetabolismDorsomedial Hypothalamic NucleusEnergy MetabolismFemaleGABAergic NeuronsGlutamineHibernationHypothalamusMaleMiceNeural PathwaysOxygen ConsumptionGlutamine

Identifiers

PMID32528181
OpenAlexW3034267508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.