Evidence map›Paper›PMID 32527956›Full record

ArticleJournal of medical genetics2021

Absence of SCAPER causes male infertility in humans and

Ohad Wormser, Ygal Levy, Anna Bakhrat, Silvia Bonaccorsi, Lucia Graziadio, Maurizio Gatti, Ali AbuMadighem, Richard J McKenney, Kyoko Okada, Saad El Riati and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. The role of chromosome/kinetochore-driven microtubule generation in Drosophila spindle assembly.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2025
    Review
  3. Article
  4. Functional assays inGenome research · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Ohad Wormser *The Morris Kahn Laboratory of Human Genetics, National Institute for Biotechnology in the Negev and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Ygal Levy *Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Anna BakhratDepartment of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Silvia BonaccorsiDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza University of Rome, Rome, Italy.
Lucia GraziadioDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza University of Rome, Rome, Italy.
Maurizio GattiDipartimento di Biologia e Biotecnologie "C. Darwin", Sapienza University of Rome, Rome, Italy.
Ali AbuMadighemShraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev Faculty of Health Sciences, Beer-Sheva, Israel.
Richard J McKenneyDepartment of Molecular and Cellular Biology, UC Davis, Davis, California, USA.
Kyoko OkadaDepartment of Molecular and Cellular Biology, UC Davis, Davis, California, USA.
Saad El RiatiSouthern District, Clalit Health Services, Beer-Sheva, Israel.
Iris Har-VardiThe Center of Advanced Research and Education in Reproduction (CARER), Ben-Gurion University of the Negev Faculty of Health Sciences, Beer-Sheva, Israel.
Mahmoud HuleihelShraga Segal Department of Microbiology, Immunology and Genetics, Ben-Gurion University of the Negev Faculty of Health Sciences, Beer-Sheva, Israel.
Eliahu Levitas *The Center of Advanced Research and Education in Reproduction (CARER), Ben-Gurion University of the Negev Faculty of Health Sciences, Beer-Sheva, Israel.
Ohad S Birk *The Morris Kahn Laboratory of Human Genetics, National Institute for Biotechnology in the Negev and Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel abdu@bgu.ac.il obirk@bgu.ac.il.
Uri Abdu *Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel abdu@bgu.ac.il obirk@bgu.ac.il.ORCID 0000-0003-1226-0750
Ben-Gurion University of the Negev · ILSapienza University of Rome · ITUniversity of California, Davis · USClalit Health Services · ILInstitute of Molecular Biology and Pathology · IT

Funding

Coordination of molecular motor activity in intracellular transport and assembly of cytoskeletal architecture.R35GM124889 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Richard James McKenney · 2017 to 2026
$4.3M
NIGMS NIH HHS R35 GM124889
6 · The paper itself

Abstract

backgroundMutation

methodsHuman clinical phenotyping, surgical testicular sperm extraction and testicular tissue staining. Generation and analysis of

resultsWe show that patients homozygous for a

conclusionsOur results show that

Indexed as

AnimalsCarrier ProteinsChromosome SegregationDisease Models, AnimalDrosophila melanogasterGenetic Predisposition to DiseaseHumansInfertility, MaleMaleMeiosisMicrotubulesMutationSerine EndopeptidasesSpermatocytesSpindle ApparatusTestisCarrier ProteinsSCAPER protein, humanSerine EndopeptidasesStomoxys serine protease 3clinical geneticsreproductive medicine

Identifiers

PMID32527956
PMCPMC10405349
OpenAlexW3034568197

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.