Evidence map›Paper›PMID 32527935›Full record

ArticleDevelopment (Cambridge, England)2020

Transcriptional repression of Myc underlies the tumour suppressor function of AGO1 in

Olga Zaytseva, Naomi C Mitchell, Linna Guo, Owen J Marshall, Linda M Parsons, Ross D Hannan, David L Levens, Leonie M Quinn

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Olga ZaytsevaDepartment of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.ORCID 0000-0001-9684-6382
Naomi C MitchellDepartment of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.
Linna GuoDepartment of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.
Owen J MarshallUniversity of Tasmania, Hobart, Tasmania 7000, Australia.
Linda M ParsonsUniversity of Tasmania, Hobart, Tasmania 7000, Australia.
Ross D HannanDepartment of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia.
David L LevensCenter for Cancer Research, National Cancer Institute, NIH, Bethesda, MD 20892, USA.
Leonie M QuinnDepartment of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2600, Australia leonie.quinn@anu.edu.au.ORCID 0000-0002-3911-6508
Australian National University · AUUniversity of Tasmania · AUNational Cancer Institute · US

Funding

Mechanisms of transcription factor integration at the c-myc promoterZIASC009144 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI LEVENS, DAVID L. · 2009 to 2025
$9.5M
6 · The paper itself

Abstract

Here, we report novel tumour suppressor activity for the

Indexed as

AnimalsAnimals, Genetically ModifiedArgonaute ProteinsDNA-Binding ProteinsDrosophilaDrosophila ProteinsLarvaMicroRNAsMutagenesis, Site-DirectedPromoter Regions, GeneticRibosomesRNA-Binding ProteinsRNA InterferenceRNA, MessengerRNA Polymerase IITranscription FactorsAGO1 protein, DrosophilaArgonaute ProteinsDNA-Binding ProteinsDrosophila ProteinsMicroRNAsMyc protein, DrosophilaPSI protein, DrosophilaRNA-Binding ProteinsRNA, MessengerRNA Polymerase IITranscription FactorsArgonauteDrosophilaMycProliferationPsiTranscription

Identifiers

PMID32527935
PMCPMC7295588
OpenAlexW3034865042

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.