Evidence map›Paper›PMID 32527722›Full record

ArticleThe Journal of biological chemistry2020

A conserved evolutionary mechanism permits Δ9 desaturation of very-long-chain fatty acyl lipids.

Yuanheng Cai, Xiao-Hong Yu, Jin Chai, Chang-Jun Liu, John Shanklin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yuanheng CaiBiochemistry & Cell Biology Department, Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0003-3699-3115
Xiao-Hong YuBiochemistry & Cell Biology Department, Stony Brook University, Stony Brook, New York, USA.ORCID 0000-0003-2352-2023
Jin ChaiBiology Department, Brookhaven National Laboratory, Upton, New York, USA.ORCID 0000-0002-4760-5811
Chang-Jun LiuBiology Department, Brookhaven National Laboratory, Upton, New York, USA.ORCID 0000-0001-6189-8756
John ShanklinBiochemistry & Cell Biology Department, Stony Brook University, Stony Brook, New York, USA shanklin@bnl.gov.ORCID 0000-0002-6774-8043
Brookhaven National Laboratory · USStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Δ9 fatty acyl desaturases introduce a

Indexed as

Biological EvolutionLipid MetabolismAmino Acid SubstitutionFatty Acid DesaturasesMutationSubstrate SpecificityFatty Acid Desaturaseschain length specificitydesaturaseenzymeenzyme mutationfatty acid metabolismmetalloenzymemonoenephospholipidstearoyl-CoA desaturasestructural determinantssubstrate specificityvery-long-chain fatty acidΔ9 integral membrane desaturase

Identifiers

PMID32527722
PMCPMC7415989
OpenAlexW3034712806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.