Evidence map›Paper›PMID 32527171›Full record

ReviewThe Journal of international medical research2020

Fecal microbiota transplantation in the treatment of intestinal steroid-resistant graft-versus-host disease: two case reports and a review of the literature.

Monika Maria Biernat, Donata Urbaniak-Kujda, Jarosław Dybko, Katarzyna Kapelko-Słowik, Iwona Prajs, Tomasz Wróbel

Registry-linked trialOpen access · goldAbstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07172191 (Manipulation of the Enteral Microbiome by Fecal Microbiota Transplantation Among Adult Patients With Malignant Hematological Diseases), which is not on this map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07172191 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Manipulation of the Enteral Microbiome by Fecal Microbiota Transplantation Among Adult Patients With Malignant Hematological Diseases

TypeinterventionalSponsorDel-Pest Central Hospital - National Institute of Hematology and Infectious DiseasesRan2025 to 2030Enrolled100ConditionsMalignant Hematologic NeoplasmArmsFecal Microbial Transplantation
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Monika Maria BiernatDepartment and Clinic of Haematology, Blood Neoplasms, and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.ORCID https://orcid.org/0000-0003-3161-3398
Donata Urbaniak-KujdaDepartment and Clinic of Haematology, Blood Neoplasms, and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Jarosław DybkoDepartment and Clinic of Internal and Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland.
Katarzyna Kapelko-SłowikDepartment and Clinic of Haematology, Blood Neoplasms, and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Iwona PrajsDepartment and Clinic of Haematology, Blood Neoplasms, and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Tomasz WróbelDepartment and Clinic of Haematology, Blood Neoplasms, and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute graft-versus-host disease (aGvHD) reduces the efficiency and safety of allogeneic hematopoietic stem cell transplantation (allo-HSCT). In recent years, attempts have been made to transplant fecal microbiota from healthy donors to treat intestinal GvHD. This study presented two cases of patients undergoing allo-HSCT who were later selected for fecal microbiota transplantation (FMT). In the first patient, FMT resulted in the complete resolution of symptoms, whereas therapeutic efficacy was not achieved in the second patient. FMT eliminated drug-resistant pathogens, namely very drug-resistant

Indexed as

Fecal Microbiota TransplantationAdultBiopsyDrug ResistanceDysbiosisFatal OutcomeGastrointestinal MicrobiomeGlucocorticoidsGraft vs Host DiseaseHematopoietic Stem Cell TransplantationHumansIntestinal MucosaLeukemia, Myeloid, AcuteMalePrimary MyelofibrosisTransplantation, HomologousGlucocorticoidsacute graft-versus-host diseaseallogeneic hematopoietic stem cell transplantationantibioticsIntestinal microfloramultidrug resistancemultiorgan failuretreatment

Identifiers

PMID32527171
PMCPMC7294377
OpenAlexW3034297084

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.