Evidence map›Paper›PMID 32527048›Full record

ArticleMicroorganisms2020

Recovery of Vaginal Microbiota After Standard Treatment for Bacterial Vaginosis Infection: An Observational Study.

Liisa Lehtoranta, Ashley A Hibberd, Jenni Reimari, Jouni Junnila, Nicolas Yeung, Johanna Maukonen, Gordon Crawford, Arthur C Ouwehand

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Contribution ofFrontiers in cellular and infection microbiology · 2021
    Pooled it
  2. Orally administratedFrontiers in immunology · 2023
    Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Current infectious disease reports · 2023
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. VaginalFrontiers in cellular and infection microbiology · 2022
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Liisa LehtorantaGlobal Health and Nutrition Science, DuPont Nutrition & Biosciences, Sokeritehtaantie 20, FIN-02460 Kantvik, Finland.
Ashley A HibberdGenomics & Microbiome Science, DuPont Nutrition & Biosciences, 4300 Duncan Avenue, Saint Louis, MO 63110, USA.
Jenni ReimariGlobal Health and Nutrition Science, DuPont Nutrition & Biosciences, Sokeritehtaantie 20, FIN-02460 Kantvik, Finland.
Jouni JunnilaPharma Ltd., Arkadiankatu 7, 00100 Helsinki, Finland.
Nicolas YeungGlobal Health and Nutrition Science, DuPont Nutrition & Biosciences, Sokeritehtaantie 20, FIN-02460 Kantvik, Finland.
Johanna MaukonenGlobal Health and Nutrition Science, DuPont Nutrition & Biosciences, Sokeritehtaantie 20, FIN-02460 Kantvik, Finland.
Gordon CrawfordCPS Research, 3 Todd Campus, West of Scotland Science Park, Glasgow G20 0SP, UK.
Arthur C OuwehandGlobal Health and Nutrition Science, DuPont Nutrition & Biosciences, Sokeritehtaantie 20, FIN-02460 Kantvik, Finland.
DuPont (Finland) · FICPS Research · GBDuPont (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaginal microbiota dysbiosis and bacterial vaginosis (BV) affect negatively women's health. Understanding vaginal microbiota fluctuations in BV during and after antibiotic treatment would facilitate accurate decision-making on the treatment regimen, avoid unnecessary antibiotic use, and potentially mitigate recurrence. We investigated vaginal microbiota composition of 30 women with BV before and after 5-day metronidazole treatment and compared the results with 30 healthy women. Vaginal microbiota was assessed by Nugent score and analyzed by 16S rRNA gene sequencing in swabs on baseline Day 1, and on Day 8 and 15, after completion of antibiotic treatment by women with BV. Prior to antibiotic treatment (Day 1), BV-positive women were dominated by

Indexed as

bacterial vaginosisLactobacillusNugent scorevaginal microbiota

Identifiers

PMID32527048
PMCPMC7355544
OpenAlexW3035311258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.