Evidence map›Paper›PMID 32527038›Full record

ArticleJournal of clinical medicine2020

Adverse Drug Reactions in the Emergency Department: Is There a Role for Pharmacogenomic Profiles at Risk?-Results from the ADRED Study.

Katja S Just, Harald Dormann, Marlen Schurig, Miriam Böhme, Jochen Fracowiak, Michael Steffens, Catharina Scholl, Thomas Seufferlein, Ingo Gräff, Matthias Schwab and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Katja S JustInstitute of Clinical Pharmacology, University Hospital of RWTH Aachen, 52074 Aachen, Germany.ORCID 0000-0002-6782-8078
Harald DormannCentral Emergency Department, Hospital Fürth, 90766 Fürth, Germany.ORCID 0000-0002-6993-8836
Marlen SchurigResearch Department, Federal Institute for Drugs and Medical Devices, 53175 Bonn, Germany.
Miriam BöhmeResearch Department, Federal Institute for Drugs and Medical Devices, 53175 Bonn, Germany.
Jochen FracowiakResearch Department, Federal Institute for Drugs and Medical Devices, 53175 Bonn, Germany.
Michael SteffensResearch Department, Federal Institute for Drugs and Medical Devices, 53175 Bonn, Germany.ORCID 0000-0002-6445-8593
Catharina SchollResearch Department, Federal Institute for Drugs and Medical Devices, 53175 Bonn, Germany.ORCID 0000-0002-1463-5619
Thomas SeufferleinInternal Medicine Emergency Department, Ulm University Medical Centre, 89081 Ulm, Germany.
Ingo GräffInterdisciplinary Emergency Department (INZ), University Hospital of Bonn, 53127 Bonn, Germany.ORCID 0000-0002-6976-1735
Matthias SchwabDr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.
Julia C StinglInstitute of Clinical Pharmacology, University Hospital of RWTH Aachen, 52074 Aachen, Germany.
Federal Institute for Drugs and Medical Devices · DERWTH Aachen University · DEDr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology · DEKlinikum Fürth · DEUniversity Hospital Bonn · DE

Funding

Bundesministerium für Gesundheit ZMVI5-2514ATA004
6 · The paper itself

Abstract

Individual differences in required drug dosages exist based on the pharmacogenomic (PGx) profiles. This study aimed to assess associations between PGx profiles and adverse drug reactions (ADR) that lead to admissions to the emergency department (ED). ADR cases of the prospective multi-center observational trial in EDs (ADRED study) were analyzed (

Indexed as

adverse drug reactionsclopidogrelCYP2C19pharmacogenomicsphenprocoumon

Identifiers

PMID32527038
PMCPMC7355597
OpenAlexW3035593400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.