Evidence map›Paper›PMID 32526922›Full record

ArticleAntioxidants (Basel, Switzerland)2020

Structure-Dependent Effects of Bisphosphonates on Inflammatory Responses in Cultured Neonatal Mouse Calvaria.

Keiko Suzuki, Sadaaki Takeyama, Shinobu Murakami, Masahiro Nagaoka, Mirei Chiba, Kaoru Igarashi, Hisashi Shinoda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Keiko SuzukiDepartment of Dental Pharmacology, School of Dentistry, Showa University, Tokyo 142-8555, Japan.
Sadaaki TakeyamaDepartment of Molecular Cell Pharmacology, Graduate School of Dental Medicine, Hokkaido University, Sapporo 060-8586, Japan.
Shinobu MurakamiCenter for Environmental Dentistry, Graduate School of Dentistry, Tohoku University, Sendai 980-8575, Japan.
Masahiro NagaokaDepartment of Dental Pharmacology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan.
Mirei ChibaDivision of Oral Physiology, Tohoku University Graduate School of Dentistry, Sendai 980-8575, Japan.
Kaoru IgarashiDivision of Craniofacial Anomalies, Tohoku University Graduate School of Dentistry, Sendai 980-8575, Japan.ORCID 0000-0003-0017-357X
Hisashi ShinodaCenter for Environmental Dentistry, Graduate School of Dentistry, Tohoku University, Sendai 980-8575, Japan.
Tohoku University · JPHokkaido University · JPOhu University · JPShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphosphonates (BPs) are classified into two groups, according to their side chain structures, as nitrogen-containing BPs (NBPs) and non-nitrogen-containing BPs (non-NBPs). In this study, we examined the effects of NBPs and non-NBPs on inflammatory responses, by quantifying the inflammatory mediators, prostaglandin E

Indexed as

anti-inflammatoryantioxidantbisphosphonatebisphosphonate-related osteonecrosis of the jaw (BRONJ)NF-κBnitrotyrosineNOperiodontitisperoxynitritePGE2

Identifiers

PMID32526922
PMCPMC7346192
OpenAlexW3035350833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.