Evidence map›Paper›PMID 32526874›Full record

ArticlePharmaceutics2020

Key-Protease Inhibition Regimens Promote Tumor Targeting of Neurotensin Radioligands.

Panagiotis Kanellopoulos, Aikaterini Kaloudi, Marion de Jong, Eric P Krenning, Berthold A Nock, Theodosia Maina

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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  7. Optimizing the Profile of [International journal of molecular sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Panagiotis KanellopoulosMolecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15341 Athens, Greece.
Aikaterini KaloudiMolecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15341 Athens, Greece.
Marion de JongDepartment of Radiology & Nuclear Medicine Erasmus MC, 3015 CN Rotterdam, Netherlands.
Eric P KrenningCyclotron Rotterdam BV, Erasmus MC, 3015 CE Rotterdam, Netherlands.
Berthold A NockMolecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15341 Athens, Greece.ORCID 0000-0002-6028-9112
Theodosia MainaMolecular Radiopharmacy, INRASTES, NCSR "Demokritos", 15341 Athens, Greece.ORCID 0000-0002-1123-2486
National Centre of Scientific Research "Demokritos" · GRErasmus MC · NLUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurotensin subtype 1 receptors (NTS1R) represent attractive molecular targets for directing radiolabeled neurotensin (NT) analogs to tumor lesions for diagnostic and therapeutic purposes. This approach has been largely undermined by the rapid in vivo degradation of linear NT-based radioligands. Herein, we aim to increase the tumor targeting of three

Indexed as

99mTc-radiotracerangiotensin-converting enzyme-inhibitorneprilysin-inhibitorneurotensinneurotensin subtype 1 receptorprotease-inhibitiontumor targeting

Identifiers

PMID32526874
PMCPMC7356968
OpenAlexW3035445921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.