ArticleNucleic acids research2020
Allostery of DNA nanostructures controlled by enzymatic modifications.
Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Spring-loaded DNA origami arrays as energy-supplied hardware for modular nanorobots.Science robotics · 2025Article
- Hierarchical access to encoded data on DNA nanostructures using administrator and user keys.Nucleic acids research · 2025Article
- Ligation-induced DNA self-assembly.Nucleic acids research · 2025Article
- Controlled mechanochemical coupling of anti-junctions in DNA origami arrays.Nature communications · 2024Article
- Synthetic molecular switches driven by DNA-modifying enzymes.Nature communications · 2024Article
- Article
- Reconfiguration of DNA nanostructures induced by enzymatic ligation treatment.Nucleic acids research · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allostery is comprehensively studied for natural macromolecules, such as proteins and nucleic acids. Here, we present controllable allostery of synthetic DNA nanostructure-enzyme systems. Rational designs of the synthetic allosteric systems are based on an in-depth understanding of allosteric sites with several types of strand placements, whose varying stacking strengths determine the local conformation and ultimately lead to a gradient level of allosteric transition. When enzymes in a molecular cloning toolbox such as DNA polymerase, exonuclease and ligase are applied to treat the allosteric sites, the resulting local conformational changes propagate through the entire structure for a global allosteric transition.
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Registered trials
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