ReviewCurrent molecular pharmacology2021
Pain Perception and Management: Where do We Stand?
Review in Current molecular pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Effect of Dinalbuphine sebacate on postoperative multimodal analgesic strategy in video-assisted thoracoscopic surgery: a double-blind randomized controlled trial.BMC anesthesiology · 2025Trial
- Prognostic factors for pain relief after CT-guided radiofrequency ablation of osteoid osteoma: a 13-year retrospective study.Skeletal radiology · 2026Article
- A Pain Memory "Trace": Cumulative Pain Perception and Damping During Fight-or-Flight Response Modeled with a Lotka-Volterra-Style Coupled Feedback Control Loop System.Journal of pain research · 2026Article
- Latent Cognitive Profiles Predict 1-Year Mental Health, Insomnia, Falls, Daily Functioning, and Pain in US Older Adults: A National Longitudinal Study.Journal of the American Medical Directors Association · 2025Article
- Exploring Cannabidiol's Role in Regenerative Medicine: Focus on Neural and Skeletal Tissues.Biomedicines · 2025Review
- Synergistic effects of chronic pain and diabetes on cardiovascular disease risk: findings from a nationwide cohort study.BMC public health · 2025Article
- Inflammatory pain and electroacupuncture: how the P2X3 receptor can help modulate inflammation-a review of current literature.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Review
- A Pluripotent Progression of the Gate Control System Theory of Pain - Modeling Ascending & Descending Pain Pathways as a Lotka-Volterra Coupled Control & Feedback Loop.Journal of pain research · 2025Article
- Modelling Pain Perception Using Fuzzy Cognitive Maps.Journal of pain research · 2025Article
- Effects of Combined Shinbaro and Celecoxib in a Complete Freund's Adjuvant-Induced Inflammatory Pain Mouse Model.Journal of inflammation research · 2025Article
- Wound infection and pain one month after trauma: an underestimated threat.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Nanotechnology in Pain Management.Pharmaceutics · 2024Review
- Anti-inflammatory and analgesic properties of Polyphyllin VI revealed by network pharmacology and RNA sequencing.Purinergic signalling · 2024Article
- The Role of the Thalamus in Nociception: Important but Forgotten.Brain sciences · 2024Review
- Unraveling the Potential of Electroanalgesia: A Literature Review of Current Therapeutics.Cureus · 2024Review
- Effect of Whole-Body Vibration Exercise on Pain, Disability, Balance, Proprioception, Functional Performance and Quality of Life in People with Non-Specific Chronic Low Back Pain: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Pathophysiology of Pain and Mechanisms of Neuromodulation: A Narrative Review (A Neuron Project).Journal of pain research · 2024Review
- Spinal antinociceptive effect of the PnTx4(5-5) peptide is possibly mediated by the NMDA autoreceptors.The journal of venomous animals and toxins including tropical diseases · 2024Article
- Commonly encountered symptoms and their management in patients with cirrhosis.Frontiers in medicine · 2024Review
- Sodium Leak Channel in Glutamatergic Neurons of the Lateral Parabrachial Nucleus Modulates Inflammatory Pain in Mice.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundPain is often flammable, sharp and sometimes described as an electrical shock. It can be categorized in three different ways as nociceptive, neuropathic and inflammatory. Nociceptive pain always originates in specific situations such as in trauma. Neuropathic pain results in nerve damage. In inflammatory pain, inflammatory mediators are involved in the sensitization of nociceptors. It is important to control the pain as it affects the individual physically, mentally, and socially.
objectiveRecognizing pain physiopathology and pain pathways, defining the relationship between receptor and transmitter is critical in developing new treatment strategies. In this review, current information on the definitions, classifications, and physiological and chemical mechanisms involved in pain are reviewed.
methodsVarious search engines were used to gather related articles/information. Only peer-reviewed journals were considered. Additional, books/chapters of standard publishers were also included in the article.
resultsWith a better understanding of the physiological and chemical mechanisms that play a role in pain, significant improvements have been made in pain treatment. Various oral or intravenous drugs, local injection treatments, physical and occupational therapy, electrical stimulation, alternative medicine applications, psychological support, and surgical applications are routinely performed in the treatment, dependent upon the type, severity and cause of the pain.
conclusionImproved understanding of pain physiopathology will serve as the basis for future improvements in the delivery of efficacious and reliable treatments, and is likely to rely on novel technological innovations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.