Evidence map›Paper›PMID 32525468›Full record

Observational studyInternational journal of stroke : official journal of the International Stroke Society2020

Impact of COVID-19 outbreak on ischemic stroke admissions and in-hospital mortality in North-West Spain.

Herbert Tejada Meza, Álvaro Lambea Gil, Agustín Sancho Saldaña, Maite Martínez-Zabaleta, Patricia de la Riva Juez, Elena López-Cancio Martínez, María Castañón Apilánez, María Herrera Isasi, Juan Marta Enguita, Mercedes de Lera Alfonso and 23 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in International journal of stroke : official journal of the International Stroke Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Stroke network performance during the first COVID-19 pandemic stage: A meta-analysis based on stroke network models.International journal of stroke : official journal of the International Stroke Society · 2021
    Pooled it
  3. Article
  4. Neurologic features in hospitalized patients with COVID-19: a prospective cohort in a catalan hospital.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  5. Article
  6. Global stroke statistics 2023: Availability of reperfusion services around the world.International journal of stroke : official journal of the International Stroke Society · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Observational
  12. Article
  13. [Open data for monitoring COVID-19 in Spain: descriptive study].Enfermedades infecciosas y microbiologia clinica · 2022
    Article
  14. Article
  15. Maintained acute stroke admission during the first wave COVID-19 pandemic in Sweden, a register-based study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  16. Article
  17. Clinical Characteristics of Patients with Acute Ischemic Stroke Previously Vaccinated Against COVID-19.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Observational
  18. Article
  19. Article
  20. Social Distancing, Stroke Admissions and Stroke Mortality During the COVID-19 Pandemic: A Multicenter, Longitudinal Study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Herbert Tejada MezaStroke Unit, Department of Neurology, 16488Hospital Universitario Miguel Servet, Zaragoza, Spain.ORCID 0000-0002-6506-1037
Álvaro Lambea GilStroke Unit, Department of Neurology, 16488Hospital Universitario Miguel Servet, Zaragoza, Spain.ORCID 0000-0003-1785-9201
Agustín Sancho SaldañaStroke Unit, Department of Neurology, 16488Hospital Universitario Miguel Servet, Zaragoza, Spain.
Maite Martínez-ZabaletaDepartment of Neurology, Hospital Universitario Donostia-Donostia Ospitalea, San Sebastián, Spain.
Patricia de la Riva JuezDepartment of Neurology, Hospital Universitario Donostia-Donostia Ospitalea, San Sebastián, Spain.
Elena López-Cancio MartínezDepartment of Neurology, 16474Hospital Universitario Central de Asturias, Oviedo, Spain.
María Castañón ApilánezDepartment of Neurology, 16474Hospital Universitario Central de Asturias, Oviedo, Spain.
María Herrera IsasiDepartment of Neurology, 83011Complejo Hospitalario de Navarra, Pamplona, Spain.
Juan Marta EnguitaDepartment of Neurology, 83011Complejo Hospitalario de Navarra, Pamplona, Spain.
Mercedes de Lera AlfonsoDepartment of Neurology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Juan F ArenillasDepartment of Neurology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.ORCID 0000-0001-7464-6101
Jon Segurola OlaizolaStroke Unit, Department of Neurology, Hospital Universitario de Araba, Vitoria, Spain.
Juan José Timiraos FernándezStroke Unit, Department of Neurology, Hospital Universitario de Araba, Vitoria, Spain.
Joaquín SánchezDepartment of Neurology, Complejo Hospitalario Universitario de Vigo, Vigo, Spain.
Mar Castellanos-RodrigoA Coruña Biomedical Research Institute, Department of Neurology, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.
Alexia RoelA Coruña Biomedical Research Institute, Department of Neurology, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.
Ignacio Casado MenéndezDepartment of Neurology, Hospital Universitario de Cabueñes, Gijón, Spain.
Mar FreijoNeurovascular group, Biocruces Bizkaia Health Research Institute, Osakidetza, Department of Neurology, Hospital Universitario Cruces, Barakaldo, Spain.
Alain Luna RodriguezNeurovascular group, Biocruces Bizkaia Health Research Institute, Osakidetza, Department of Neurology, Hospital Universitario Cruces, Barakaldo, Spain.
Enrique Palacio PortillaDepartment of Neurology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Yésica Jiménez LópezDepartment of Neurology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Emilio Rodríguez CastroDepartment of Neurology, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Susana Arias RivasDepartment of Neurology, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
Javier Tejada GarcíaDepartment of Neurology, Complejo Asistencial Universitario de León, León, Spain.
Iria Beltrán RodríguezDepartment of Neurology, Complejo Asistencial Universitario de León, León, Spain.
Francisco Julián-VillaverdeDepartment of Neurology, 118003Hospital San Pedro, La Rioja, Spain.
Maria Pilar Moreno GarcíaDepartment of Neurology, 118003Hospital San Pedro, La Rioja, Spain.
José María Trejo-Gabriel-GalánDepartment of Neurology, Complejo Asistencial Universitario de Burgos, Burgos, Spain.ORCID 0000-0001-9591-8452
Ana Echavarría IñiguezDepartment of Neurology, Complejo Asistencial Universitario de Burgos, Burgos, Spain.
Carlos Tejero JusteDepartment of Neurology, Hospital Clínico Lozano Blesa, Zaragoza, Spain.
Cristina Pérez LázaroDepartment of Neurology, Hospital Clínico Lozano Blesa, Zaragoza, Spain.
Javier Marta MorenoStroke Unit, Department of Neurology, 16488Hospital Universitario Miguel Servet, Zaragoza, Spain.
On Behalf Of The Nordictus Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSpain has been one of the countries heavily stricken by COVID-19. But this epidemic has not affected all regions equally. We analyzed the impact of the COVID-19 pandemic on hospital stroke admissions and in-hospital mortality in tertiary referral hospitals from North-West Spain.

methodsSpanish multicenter retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. We recorded the number of patients admitted for ischemic stroke between 30 December 2019 and 3 May 2020, the number of IVT and EVT procedures, and in-hospital mortality.

resultsIn the study period, 2737 patients were admitted with ischemic stroke. There was a decrease in the weekly mean admitted patients during the pandemic (124 vs. 173, p<0.001). In-hospital mortality of stroke patients increased significantly (9.9% vs. 6.5%, p = 0.003), but there were no differences in the proportion of IVT (17.3% vs. 16.1%, p = 0.405) or EVT (22% vs. 23%, p = 0.504).

conclusionWe found a decrease in the number of ischemic stroke admissions and an increase in in-hospital mortality during the COVID-19 epidemic in this large study from North-West Spain. There were regional changes within the network, not fully explained by the severity of the pandemic in different regions.

Indexed as

BetacoronavirusAgedBrain IschemiaCoronavirus InfectionsCOVID-19FemaleHospitalizationHospital MortalityHumansMalePandemicsPneumonia, ViralReperfusionRetrospective StudiesSARS-CoV-2SpainCOVID-19ischemic strokemortalitySpainStrokestroke care

Identifiers

PMID32525468
PMCPMC7322514

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.