Evidence map›Paper›PMID 32525457›Full record

ArticleEmerging microbes & infections2020

Unbalanced production of LTB

Icaro Bonyek-Silva, Sara Nunes, Reinan L Santos, Filipe R Lima, Alexsandro Lago, Juliana Silva, Lucas P Carvalho, Sergio M Arruda, Henrique C Serezani, Edgar M Carvalho and 2 more

Open access · goldAbstract read
In one paragraph

Article in Emerging microbes & infections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. An underlying mechanism of bovine mastitis: PGEThe veterinary quarterly · 2026
    Article
  2. Review
  3. Article
  4. High glucose heightens vulnerability toEmerging microbes & infections · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Prostaglandin E2 contributes toEmerging microbes & infections · 2023
    Article
  11. Article
  12. LTBDiabetes · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Icaro Bonyek-SilvaGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Sara NunesGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Reinan L SantosGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Filipe R LimaGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Alexsandro LagoFederal University of Bahia (UFBA), Salvador, Brazil.
Juliana SilvaFederal University of Bahia (UFBA), Salvador, Brazil.
Lucas P CarvalhoGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Sergio M ArrudaGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Henrique C SerezaniDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Edgar M CarvalhoGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Claudia I BrodskynGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Natalia M TavaresGonçalo Moniz Institute, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Brazil.
Universidade Federal da Bahia · BRFundação Oswaldo Cruz · BRNational Institute of Science and Technology · IDVanderbilt University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Poorly controlled diabetes mellitus leads to several comorbidities, including susceptibility to infections. Hyperglycemia increases phagocyte responsiveness, however immune cells from people with diabetes show inadequate antimicrobial functions. We and others have shown that aberrant production of leukotriene B

Indexed as

BrazilCells, CulturedComorbidityCross-Sectional StudiesDiabetes MellitusDinoprostoneHumansInterleukin-6Leishmania braziliensisLeishmaniasis, CutaneousLeukotriene B4MacrophagesPhagocytesReactive Oxygen SpeciesTumor Necrosis Factor-alphaDinoprostoneIL6 protein, humanInterleukin-6Leukotriene B4Reactive Oxygen SpeciesTNF protein, humanTumor Necrosis Factor-alphaDiabeteshuman leishmaniasisLeishmania braziliensislipid mediatorsLTB4PGE2

Identifiers

PMID32525457
PMCPMC7473187
OpenAlexW3033162353

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.