Evidence map›Paper›PMID 32525131›Full record

ArticleActa bio-medica : Atenei Parmensis2020

Hodgkin's lymphoma: post- autologous transplantation consolidation therapy.

Francesco Merli, Filippo Ballerini, Barbara Botto, Manuel Gotti, Vincenzo Pavone, Alessandro Pulsoni, Pietro Maria Stefani, Fulvio Massaro, Simonetta Viviani

Open access · greenAbstract readCase Reports
In one paragraph

Article in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Francesco MerliHematology Unit, Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy. Francesco.Merli@ausl.re.it.
Filippo BalleriniClinic of Hematology, Department of Internal Medicine (DiMI), University of Genoa, Italy; S. Martino Hospital IRCCS, Genoa, Italy . ballerini@unige.it.
Barbara BottoDipartimento di Oncologia ed Ematologia, A.O Città della Salute e della Scienza di Torino, San Giovanni Battista. Torino, Italy . bbotto@cittadellasalute.to.it.
Manuel GottiDepartment of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. manuel.gotti@hotmail.it.
Vincenzo PavoneDept. of Molecular and Developmental Medicine, University of Siena, Siena, Italy. salentoematologia@piafondazionepanico.it.
Alessandro PulsoniDepartment of Cellular Biotechnologies and Hematology, La Sapienza University, Rome, Italy. pulsoni@bce.uniroma1.it.
Pietro Maria StefaniUnit of Hematology, Ca' Foncello Hospital, Treviso, Italy. pmstefani@ulss.tv.it.
Fulvio MassaroHematology Unit, Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy. Francesco.Merli@ausl.re.it.
Simonetta VivianiOnco-Hematology Division, IEO, European Institute of Oncology, IRCCS, Milan, Italy. Simonetta.Viviani@ieo.it.
Azienda Sanitaria Unità Locale di Reggio Emilia · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITCa' Foncello Hospital · ITEuropean Institute of Oncology · ITMartin University · USPoliclinico San Matteo Fondazione · ITSapienza University of Rome · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A first-line chemotherapy program based on the ABVD regimen is currently considered the golden standard by most hematologists, being able to achieve a cure without any need of subsequent therapies in >70% of patients with advanced-stage Hodgkin's lymphoma (HL). To increase this percentage, efforts in recent decades focused on the development of new therapeutic strategies. A first major effort was the introduction of the BEACOPP chemotherapy regimen, which is able to increase the response rate and to reduce the need of salvage therapies. However, this result did not demonstrate an advantage in terms of overall survival compared to ABVD, mainly due to an excess of non lymphoma-related events in the follow-up phase. Here we describe three clinical cases of young HL patients who had relapsed/refractory disease after the induction chemotherapy. These three clinical cases provide practical and real world evidence in favor of the use of BV in monotherapy as consolidation treatment after autologous stem cells transplantation in patients with relapsed/refractory HL.

Indexed as

Stem Cell TransplantationAdultConsolidation ChemotherapyFemaleHodgkin DiseaseHumansNeoplasm Recurrence, LocalTransplantation, AutologousYoung Adult

Identifiers

PMID32525131
PMCPMC7944651
OpenAlexW3033051877

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.