Evidence map›Paper›PMID 32524960›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Efficacy and Safety of Pyronaridine-Artesunate for the Treatment of Uncomplicated

Kay Thwe Han, Khin Lin, Zay Yar Han, Moe Kyaw Myint, Kyin Hla Aye, Aung Thi, Badri Thapa, Maria Dorina Bustos, Isabelle Borghini-Fuhrer, Pascal Ringwald and 1 more

Open access · hybridAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Efficacy, Safety and Tolerability of Pyronaridine-artesunate in Asymptomatic Malaria-infected Individuals: a Randomized Controlled Trial.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Kay Thwe Han1Department of Medical Research, Ministry of Health and Sports, Yangon, Myanmar.
Khin Lin2Department of Medical Research (Pyin Oo Lwin Branch), Ministry of Health and Sports, Pyin Oo Lwin Township, Myanmar.
Zay Yar Han1Department of Medical Research, Ministry of Health and Sports, Yangon, Myanmar.
Moe Kyaw Myint2Department of Medical Research (Pyin Oo Lwin Branch), Ministry of Health and Sports, Pyin Oo Lwin Township, Myanmar.
Kyin Hla Aye1Department of Medical Research, Ministry of Health and Sports, Yangon, Myanmar.
Aung Thi3National Malaria Control Programme, Department of Public Health, Ministry of Health and Sports, Nay Pyi Taw, Myanmar.
Badri Thapa4World Health Organization, Yangon, Myanmar.
Maria Dorina Bustos5World Health Organization, Bangkok, Thailand.
Isabelle Borghini-Fuhrer6Medicines for Malaria Venture, Geneva, Switzerland.
Pascal Ringwald7World Health Organization, Geneva, Switzerland.
Stephan Duparc6Medicines for Malaria Venture, Geneva, Switzerland.
Ministry of Health · MMMedicines for Malaria Venture · CHMinistry of Health and Sports · MMWorld Health Organization · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four single-arm, prospective, clinical studies of pyronaridine-artesunate efficacy in uncomplicated

Indexed as

AdolescentAdultAntimalarialsArtesunateChildDrug Therapy, CombinationFemaleHumansMalaria, FalciparumMalaria, VivaxMaleMiddle AgedMyanmarNaphthyridinesPlasmodium falciparumPlasmodium vivaxAntimalarialsArtesunateNaphthyridinespyronaridine

Identifiers

PMID32524960
PMCPMC7470518
OpenAlexW3033857641

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.