Evidence map›Paper›PMID 32524881›Full record

ArticleInternational journal of immunopathology and pharmacology

Characterization of lymphocyte subsets in ascitic fluid and peripheral blood of decompensated cirrhotic patients with chronic hepatitis C and alcoholic liver disease: A pivotal study.

Roberto Giulio Romanelli, Gianfranco Vitiello, Stefano Gitto, Maria Grazia Giudizi, Roberta Biagiotti, Alessia Carraresi, Francesco Vizzutti, Giacomo Laffi, Fabio Almerigogna

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In one paragraph

Article in International journal of immunopathology and pharmacology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Roberto Giulio RomanelliInternal Medicine and Liver Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Gianfranco VitielloDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Stefano GittoInternal Medicine and Liver Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0002-8042-6508
Maria Grazia GiudiziImmunoallergology Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Roberta BiagiottiImmunoallergology Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Alessia CarraresiImmunoallergology Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Francesco VizzuttiInternal Medicine and Liver Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Giacomo LaffiInternal Medicine and Liver Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.ORCID https://orcid.org/0000-0001-6916-1134
Fabio AlmerigognaImmunoallergology Unit, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
University of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatitis C virus and alcoholic liver disease are major causes of chronic liver diseases worldwide. Little is known about differences between chronic hepatitis C and alcoholic liver disease in terms of lymphocytes' sub-population. Aim of the present study was to compare the sub-populations of lymphocytes in both ascitic compartment and peripheral blood in patients with decompensated liver cirrhosis due to chronic hepatitis C and alcoholic liver disease. Patients with decompensated liver cirrhosis due to hepatitis C virus or alcoholic liver disease evaluated from April 2014 to October 2016 were enrolled. Whole blood and ascitic fluid samples were stained with monoclonal antibodies specific for human TCRɑβ, TCRɣδ, CD3, CD4, CD8, CD19, CCR6, CD16, CD56, CD25, HLA-DR, Vɑ24. Sixteen patients with decompensated liver cirrhosis were recruited (9 with hepatitis C virus and 7 with alcoholic liver disease). In ascitic fluid, the percentage of both CD3

Indexed as

Lymphocyte SubsetsAgedAged, 80 and overAntibodies, MonoclonalAscitic FluidFemaleHepatitis CHumansKiller Cells, NaturalLiver CirrhosisLiver Cirrhosis, AlcoholicMaleMiddle AgedAntibodies, Monoclonalascitesdecompensated cirrhosisinflammatory responselymphocyte immunophenotypingnatural killer T cells

Identifiers

PMID32524881
PMCPMC7290250
OpenAlexW3033337670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.