Evidence map›Paper›PMID 32524786›Full record

ArticleKorean journal of radiology2020

CT Quantitative Analysis and Its Relationship with Clinical Features for Assessing the Severity of Patients with COVID-19.

Dong Sun, Xiang Li, Dajing Guo, Lan Wu, Ting Chen, Zheng Fang, Linli Chen, Wenbing Zeng, Ran Yang

Abstract read
In one paragraph

Article in Korean journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Dong SunDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-1975-7201
Xiang LiDepartment of Radiology, Chongqing Three Gorges Central Hospital, Chongqing, China.ORCID 0000-0002-2886-6602
Dajing GuoDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0001-8655-6621
Lan WuDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-5677-7658
Ting ChenDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0001-8328-3859
Zheng FangDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-2826-189X
Linli ChenDepartment of Radiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0001-8685-4792
Wenbing ZengDepartment of Radiology, Chongqing Three Gorges Central Hospital, Chongqing, China.ORCID 0000-0003-3579-3752
Ran YangDepartment of Radiology, Chongqing Three Gorges Central Hospital, Chongqing, China. yangran_sx@163.com.ORCID 0000-0003-3199-9104

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the value of initial CT quantitative analysis of ground-glass opacity (GGO), consolidation, and total lesion volume and its relationship with clinical features for assessing the severity of coronavirus disease 2019 (COVID-19). MATERIALS AND

methodsA total of 84 patients with COVID-19 were retrospectively reviewed from January 23, 2020 to February 19, 2020. Patients were divided into two groups: severe group (n = 23) and non-severe group (n = 61). Clinical symptoms, laboratory data, and CT findings on admission were analyzed. CT quantitative parameters, including GGO, consolidation, total lesion score, percentage GGO, and percentage consolidation (both relative to total lesion volume) were calculated. Relationships between the CT findings and laboratory data were estimated. Finally, a discrimination model was established to assess the severity of COVID-19.

resultsPatients in the severe group had higher baseline neutrophil percentage, increased high-sensitivity C-reactive protein (hs-CRP) and procalcitonin levels, and lower baseline lymphocyte count and lymphocyte percentage (

conclusionCT quantitative parameters showed strong correlations with laboratory inflammatory markers, suggesting that CT quantitative analysis might be an effective and important method for assessing the severity of COVID-19, and may provide additional guidance for planning clinical treatment strategies.

Indexed as

Tomography, X-Ray ComputedAdultAlgorithmsArea Under CurveBetacoronavirusChinaCoronavirus InfectionsCOVID-19C-Reactive ProteinFemaleHumansImage Processing, Computer-AssistedInflammationLungLymphocytesMaleC-Reactive ProteinProcalcitoninComputed tomographyConsolidationCoronavirus disease 2019Ground-glass opacityQuantitative analysisSeverity

Identifiers

PMID32524786
PMCPMC7289692

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.