Evidence map›Paper›PMID 32524521›Full record

ArticleJournal of nephrology2021

Identical twins with idiopathic membranous nephropathy.

Tian Tao, Jue Wang, Song Lei, Zhangxue Hu

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In one paragraph

Article in Journal of nephrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tian TaoDepartment of Nephrology, West China Hospital, Sichuan University, Guoxue ally 37#, Wuhou District, Chengdu City, Sichuan Province, China.
Jue WangClinical Transfusion Research Center, Institute of Blood Transfusion, CAMS & PUMC, Chengdu, Sichuan, China.
Song LeiDepartment of Pathology, West China Hospital, Sichuan University, Chengdu city, Sichuan Province, China.
Zhangxue HuDepartment of Nephrology, West China Hospital, Sichuan University, Guoxue ally 37#, Wuhou District, Chengdu City, Sichuan Province, China. hzxawy@scu.edu.cn.ORCID http://orcid.org/0000-0003-1525-2983
Sichuan University · CNGuangzhou Blood Center · CN

Funding

National Natural Science Foundation of China 81470916Sichuan Province Key Technology R&D Program 2018SZ0122
6 · The paper itself

Abstract

The pathogenesis of idiopathic membranous nephropathy is associated with autoantibodies, most often against the phospholipase A2 receptor (PLA2R) and with genetic factors, especially those involving human leukocyte antigen (HLA) genes. Idiopathic membranous nephropathy is not a typical inherited Mendelian disorder. Reports of idiopathic membranous nephropathy in twins are rare. Herein, we report on two twin sisters diagnosed with PLA2R-associated idiopathic membranous nephropathy. We identified the HLA-DRB1*0301, HLA-DRB1*1501, and HLA-DQB1*0602 alleles in the twin sisters, which were reported as independent risk alleles for idiopathic membranous nephropathy in the Asian population. This case report provides novel evidence for the role of predisposing HLA alleles in the pathogenesis of idiopathic membranous nephropathy.

Indexed as

Glomerulonephritis, MembranousAllelesAutoantibodiesHumansReceptors, Phospholipase A2Twins, MonozygoticAutoantibodiesPLA2R1 protein, humanReceptors, Phospholipase A2Anti-PLA2R antibodyHLA genesIdiopathic membranous nephropathyTwins

Identifiers

PMID32524521
OpenAlexW3033190233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.