Evidence map›Paper›PMID 32524345›Full record

ReviewJournal of microbiology (Seoul, Korea)2020

Bacterial bug-out bags: outer membrane vesicles and their proteins and functions.

Kesavan Dineshkumar, Vasudevan Aparna, Liang Wu, Jie Wan, Mohamod Hamed Abdelaziz, Zhaoliang Su, Shengjun Wang, Huaxi Xu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of microbiology (Seoul, Korea), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Streptomyces coelicolor Vesicles: Many Molecules To Be Delivered.Applied and environmental microbiology · 2022
    Article
  6. Extracellular membrane vesicles fromFrontiers in microbiology · 2022
    Article
  7. Review
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kesavan DineshkumarInternational Genomics Research Center (IGRC), Jiangsu University, Zhenjiang, 212013, P. R. China. dkspora@gmail.com.
Vasudevan AparnaInternational Genomics Research Center (IGRC), Jiangsu University, Zhenjiang, 212013, P. R. China.
Liang WuDepartment of Immunology, School of Medicine, Jiangsu University, Zhenjiang, 212013, P. R. China.
Jie WanDepartment of Immunology, School of Medicine, Jiangsu University, Zhenjiang, 212013, P. R. China.
Mohamod Hamed AbdelazizDepartment of Immunology, School of Medicine, Jiangsu University, Zhenjiang, 212013, P. R. China.
Zhaoliang SuInternational Genomics Research Center (IGRC), Jiangsu University, Zhenjiang, 212013, P. R. China.
Shengjun WangDepartment of Immunology, School of Medicine, Jiangsu University, Zhenjiang, 212013, P. R. China.
Huaxi XuInternational Genomics Research Center (IGRC), Jiangsu University, Zhenjiang, 212013, P. R. China. xuhx@ujs.edu.cn.
Jiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among the major bacterial secretions, outer membrane vesicles (OMVs) are significant and highly functional. The proteins and other biomolecules identified within OMVs provide new insights into the possible functions of OMVs in bacteria. OMVs are rich in proteins, nucleic acids, toxins and virulence factors that play a critical role in bacteria-host interactions. In this review, we discuss some proteins with multifunctional features from bacterial OMVs and their role involving the mechanisms of bacterial survival and defence. Proteins with moonlighting activities in OMVs are discussed based on their functions in bacteria. OMVs harbour many other proteins that are important, such as proteins involved in virulence, defence, and competition. Overall, OMVs are a power-packed aid for bacteria, harbouring many defensive and moonlighting proteins and acting as a survival kit in case of an emergency or as a defence weapon. In summary, OMVs can be defined as bug-out bags for bacterial defence and, therefore, survival.

Indexed as

Amino AcidsBacteriaBacterial Outer Membrane ProteinsExtracellular VesiclesHumansLipid MetabolismNucleic AcidsVirulence FactorsAmino AcidsBacterial Outer Membrane ProteinsNucleic AcidsVirulence Factorsbacterial defence mechanismbacterial survivalmoonlighting proteinsouter membrane vesiclesSOS mechanism

Identifiers

PMID32524345
OpenAlexW3034051508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.