Evidence map›Paper›PMID 32524304›Full record

ArticleJournal of gastrointestinal cancer2020

Physical Inactivity and Pancreatic Cancer Mortality.

Megha Pratapwar, Ashley E Stenzel, Janine M Joseph, Christos Fountzilas, John Lewis Etter, Jennifer M Mongiovi, Rikki Cannioto, Kirsten B Moysich

Abstract read
In one paragraph

Article in Journal of gastrointestinal cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Megha PratapwarSummer Research Experience Program in Cancer Science, Williamsville East High School, East Amherst, Buffalo, NY, USA.
Ashley E StenzelDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Elm & Carlton St, Buffalo, NY, USA.
Janine M JosephDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Elm & Carlton St, Buffalo, NY, USA.
Christos FountzilasDepartment of Gastrointestinal Medical Oncology, Roswell Park Comprehensive Cancer Center, Elm & Carlton St, Buffalo, NY, USA.
John Lewis EtterDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Elm & Carlton St, Buffalo, NY, USA.
Jennifer M MongioviDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Elm & Carlton St, Buffalo, NY, USA.
Rikki CanniotoDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Elm & Carlton St, Buffalo, NY, USA.
Kirsten B MoysichDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Elm & Carlton St, Buffalo, NY, USA. Moysich@roswellpark.org.ORCID http://orcid.org/0000-0002-4678-2058

Funding

Interdisciplinary Training in Cancer Epidemiology at UBT32CA113951 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI FREUDENHEIM, JO L., MOYSICH, KIRSTEN B. · 2017 to 2021
$693k
NCI NIH HHS T32 CA113951
6 · The paper itself

Abstract

objectiveTo determine the association between pre-diagnostic recreational physical inactivity (RPI) and pancreatic cancer (PC) mortality.

methodsThis analysis included 107 patients seen at Roswell Park Comprehensive Cancer Center diagnosed with PC between 1989 and 1998. Cox proportional hazards models were used to determine hazard ratios (HR) and 95% confidence intervals (CI) for PC mortality associated with self-reported pre-diagnostic RPI. Models were adjusted for known prognostic factors, including age, sex, stage at diagnosis, smoking status, and body mass index (BMI). Results were also stratified by sex, BMI, smoking status, histology, and treatment status.

resultsWe observed a significant association between RPI and PC mortality in all patients (HR = 1.72, 95% CI = 1.06-2.79), as well as among overweight or obese patients (HR = 2.74, 95% 95% CI = 1.42-5.29), females (HR = 2.63; 95% CI, 1.08-6.39), and non-smokers (HR = 1.72; 95% CI, 1.02-2.89).

conclusionThese results suggest that RPI prior to PC diagnosis is associated with a higher risk of death. Future studies with larger sample sizes are needed to explore whether this association varies across tumor histology.

Indexed as

Body Mass IndexSedentary BehaviorAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPancreatic NeoplasmsPrognosisRisk FactorsSurvival RateExerciseMortalityPancreatic cancerPhysical activitySurvival

Identifiers

PMID32524304
PMCPMC8221412

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.