Evidence map›Paper›PMID 32524073›Full record

ArticleTherapeutic advances in ophthalmology

Correction of perceived visual distortions using a software application and correlation to age-related macular degeneration.

Muhammad Hassan, Adithi D Chakravarthy, Mahadevan Subramaniam, Parvathi Chundi, Mohammad Ali Sadiq, Muhammad Sohail Halim, Rubbia Afridi, Anh N T Tran, Yasir J Sepah, Diana V Do and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Muhammad HassanMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.ORCID https://orcid.org/0000-0001-9033-8117
Adithi D ChakravarthyCollege of Information Science & Technology, University of Nebraska Omaha, Omaha, NE, USA.ORCID https://orcid.org/0000-0001-7064-3376
Mahadevan SubramaniamCollege of Information Science & Technology, University of Nebraska Omaha, Omaha, NE, USA.
Parvathi ChundiCollege of Information Science & Technology, University of Nebraska Omaha, Omaha, NE, USA.
Mohammad Ali SadiqKentucky Lions Eye Center, University of Louisville, Louisville, KY, USA.
Muhammad Sohail HalimMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Rubbia AfridiMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Anh N T TranMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Yasir J SepahMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Diana V DoMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, Palo Alto, CA, USA.
Quan Dong NguyenMary M. and Sash A. Spencer Center for Vision Research, Byers Eye Institute, Stanford University, 2370 Watson Court, Suite 200, Palo Alto, CA 94303, USA.
Smith-Kettlewell Eye Research Institute · USUniversity of Nebraska at Omaha · USUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the use of software-generated corrections in neutralizing perceived distortions in age-related macular degeneration.

methodsA tablet-based application was utilized to elicit distortions. Five subjects (seven eyes: neovascular age-related macular degeneration and three eyes: non-neovascular age-related macular degeneration) traced the reference lines, and their distortion traces were recorded. To counter distortion, a software-generated trace was re-traced by subjects to produce a corrected trace. Final traces were superimposed on optical coherence tomography images and following distances calculated: (a) dDT: distance between distortion trace and reference line; (b) dGT: distance between software-generated trace and corrected trace; (c) dCT: distance between corrected trace and reference line. Mean percent improvement in distortion was reported. Mean effectiveness of correction was also reported by utilizing

resultsMean age of the subjects was 76.6 (±9.5) years. Each patient traced six reference lines and each was considered a separate case. Out of 30 cases, 17 (56.6%) elicited distortion. Mean percent improvement in distortion was 71.3 ± 23% (

conclusionSoftware-generated corrections can potentially correct for perceived distortions in patients with age-related macular degeneration, especially in cases with preserved photoreceptor layer.

Indexed as

age-related macular degenerationmetamorphopsiavisual distortion

Identifiers

PMID32524073
PMCPMC7235661
OpenAlexW2737942589

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.