Evidence map›Paper›PMID 32524066›Full record

ArticlePersonality neuroscience2020

Sex differences in associations of socioemotional dispositions measured in childhood and adolescence with brain white matter microstructure 12 years later.

Benjamin B Lahey, Kendra E Hinton, Francisco Calvache Meyer, Victoria Villalta-Gil, Carol A Van Hulle, Brooks Applegate, Xiaochan Yang, David H Zald

Abstract read
In one paragraph

Article in Personality neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Benjamin B LaheyDepartment of Public Health Sciences, University of Chicago, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-0385-9676
Kendra E HintonDepartment of Psychological Sciences, Vanderbilt University, Nashville, TN, USA.
Francisco Calvache MeyerDepartment of Psychological Sciences, Vanderbilt University, Nashville, TN, USA.
Victoria Villalta-GilDepartment of Psychological Sciences, Vanderbilt University, Nashville, TN, USA.
Carol A Van HulleSchool of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Brooks ApplegateDepartment of Educational Leadership, Research, and Technology, Western Michigan University, Kalamazoo, MI, USA.
Xiaochan YangDepartment of Public Health Sciences, University of Chicago, Chicago, IL, USA.
David H ZaldDepartment of Psychological Sciences, Vanderbilt University, Nashville, TN, USA.

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
RDoC Constructs: Neural Substrates, Heritability, and Relation to PsychopathologyR01MH098098 · NIMH · VANDERBILT UNIVERSITY · PI LAHEY, BENJAMIN B, ZALD, DAVID HAROLD · 2012 to 2015
$4.4M
NCATS NIH HHS UL1 TR000430NCATS NIH HHS UL1 TR000445NIMH NIH HHS R01 MH098098
6 · The paper itself

Abstract

Predictive associations were estimated between socioemotional dispositions measured at 10-17 years using the Child and Adolescent Dispositions Scale (CADS) and future individual differences in white matter microstructure measured at 22-31 years of age. Participants were 410 twins (48.3% monozygotic) selected for later neuroimaging by oversampling on risk for psychopathology from a representative sample of child and adolescent twins. Controlling for demographic covariates and total intracranial volume (TICV), each CADS disposition (negative emotionality, prosociality, and daring) rated by one of the informants (parent or youth) significantly predicted global fractional anisotropy (FA) averaged across the major white matter tracts in brain in adulthood, but did so through significant interactions with sex after false discovery rate (FDR) correction. In females, each 1 SD difference in greater parent-rated prosociality was associated with 0.43 SD greater FA (

Indexed as

DispositionsFractional anisotropyPsychopathologySex differences

Identifiers

PMID32524066
PMCPMC7253690

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.