Evidence map›Paper›PMID 32523947›Full record

ArticleFrontiers in cell and developmental biology2020

Xiangwen Peng, Shunyang Fan, Jing Tan, Zhi Zeng, Meiling Su, Yuan Zhang, Ming Yang, Luoxing Xia, Xuejiao Fan, Weibin Cai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Signaling pathways regulating cardiac regeneration.Cell regeneration (London, England) · 2026
    Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Mechanism of CREB1 in cardiac function of rats with heart failure via regulating the microRNA-376a-3p/TRAF6 axis.Mammalian genome : official journal of the International Mammalian Genome Society · 2022
    Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Xiangwen PengGuangzhou Women and Children's Medical Centre, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.
Shunyang FanHeart Center, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Jing TanGuangdong Engineering & Technology Research Center for Disease-Model Animals, Laboratary Animal Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Zhi ZengGuangzhou Women and Children's Medical Centre, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.
Meiling SuGuangzhou Women and Children's Medical Centre, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.
Yuan ZhangGuangzhou Women and Children's Medical Centre, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.
Ming YangGuangdong Engineering & Technology Research Center for Disease-Model Animals, Laboratary Animal Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Luoxing XiaGuangzhou Women and Children's Medical Centre, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.
Xuejiao FanGuangzhou Women and Children's Medical Centre, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.
Weibin CaiGuangdong Engineering & Technology Research Center for Disease-Model Animals, Laboratary Animal Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Wai Ho TangGuangzhou Women and Children's Medical Centre, Institute of Pediatrics, Guangzhou Medical University, Guangzhou, China.
Guangzhou Medical University · CNSun Yat-sen University · CNThird Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have demonstrated that inhibition of canonical Wnt signaling promotes zebrafish heart regeneration and that treatment of injured heart tissue with the Wnt activator 6-bromo-indirubin-3-oxime (BIO) can impede cardiomyocyte proliferation. However, the mechanism by which Wnt signaling regulates downstream gene expression following heart injury remains unknown. In this study, we have demonstrated that inhibition of injury-induced myocardial

Indexed as

c-junc-jun/jnk1/creb1creb1nkx2.5nkx25wnt2bbzebrafish heart regeneration

Identifiers

PMID32523947
PMCPMC7261892
OpenAlexW3027404572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.