Evidence map›Paper›PMID 32523916›Full record

ArticleEuropean journal of case reports in internal medicine2020

Amoxicillin-Induced Aseptic Meningitis.

Débora Sousa, Pedro Raimundo

Open access · goldAbstract read
In one paragraph

Article in European journal of case reports in internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Suspected Case of Amoxicillin-Associated Aseptic Meningitis.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Débora SousaInternal Medicine Department, Hospital da Luz, Lisboa, Portugal.
Pedro RaimundoInternal Medicine Department, Hospital da Luz, Lisboa, Portugal.
Hospital da Luz · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amoxicillin is a semi-synthetic beta-lactam antibiotic that belongs to the penicillin family. It is the most prescribed antibiotic in the world. It has few side effects, even though hypersensitivity reactions may occur, with potential life-threatening effects. The authors present the case of a 63-year-old male admitted to the emergency department with a 2-week history of fever and occipital headache. The symptoms began after he started antibiotic prophylaxis with amoxicillin for a dental procedure. Cerebrospinal fluid analysis was suggestive of aseptic meningitis and the patient improved quickly after discontinuation of the drug. The patient's previous medical history highlighted a similar episode after he had started taking amoxicillin as part of a scheme for the treatment of a LEARNING POINTS: Aseptic meningitis is a rare side effect of amoxicillin.It is a diagnosis of exclusion and establishing a chronological relationship between the administration of amoxicillin and the onset of clinical symptoms is a key element for the diagnosis.The physiopathology is not well defined, but the consensus is that it is most probably the result of an immunologic hypersensitivity reaction.

Indexed as

amoxicillinAseptic meningitisdrug-induced aseptic meningitis

Identifiers

PMID32523916
PMCPMC7279912
OpenAlexW3033236348

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.