Evidence map›Paper›PMID 32523880›Full record

ArticleAvicenna journal of phytomedicine

Cardiovascular effects of standardized hydroalcoholic extract of

Ismael Hamounpeima, Reza Mohebbati, Mahmoud Hosseini, Abolfazl KhajaviRad, Hasan Rakhshandeh, Abbas Safarnejad, Mohammad Naser Shafei

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Food science & nutrition · 2024
    Article
  2. Synergic effects ofIranian journal of basic medical sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ismael HamounpeimaDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Reza MohebbatiDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahmoud HosseiniDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abolfazl KhajaviRadDepartment of Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Hasan RakhshandehPharmacological Research Center of Medicinal Plants, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abbas SafarnejadFaculty of Khorasan Razavi Agricultural and Natural Resources Research Center, Education and Extension Organization (AREEO), Mashhad, Iran.
Mohammad Naser ShafeiNeurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMATERIALS AND

methodsAnimals were assigned into the following groups: 1) Control, 2) AngII (50 ng/kg), 3) AngII + losartan (Los, 10 mg/kg) and 4-6) Doses 4, 12 and 24 mg/kg of extract +AngII groups. AngII and Los were injected intravenously and the extract was injected intraperitoneal. In

resultsIn normotensive rats, 12 mg/kg of the extract showed significant hypotensive effects while 24 mg/kg produced significant tachycardia. Increased ∆SBP and ∆MAP in AngII group were significantly blunted by Los. Doses 4 and 12 mg/kg of the plant also significantly attenuate the effect of AngII on ∆SBP and ∆MAP. Tachycardia induced by 24 mg/kg of the extract didn't affect by AngII. Extract also significantly improved the effect of AngII on MDA, total thiol content, CAT and SOD in both heart and aorta tissues.

conclusion

Indexed as

Blood pressureHerat rateHypertensionRibes khorasanicum Angiotensin II

Identifiers

PMID32523880
PMCPMC7256283
OpenAlexW2980038918

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.