Evidence map›Paper›PMID 32523864›Full record

Article3 Biotech2020

MicroRNA-155 complementation on a chemically functionalized dual electrode surface for determining breast cancer.

Subash C B Gopinath, Veeradasan Perumal, Shijin Xuan

Open access · greenAbstract read
In one paragraph

Article in 3 Biotech, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Subash C B GopinathSchool of Bioprocess Engineering, Universiti Malaysia Perlis, 02600 Arau, Perlis Malaysia.ORCID 0000-0002-8347-4687
Veeradasan PerumalMechanical Engineering Department, Universiti Teknologi PETRONAS, 32610 Seri Iskandar, Perak Darul Ridzuan Malaysia.
Shijin XuanDepartment of Mammary and Thyroid Surgery, Central Hospital Affiliated to Shandong First Medical University, No. 105 Jiefang Road, Lixia District, 250013 Jinan, Shandong Province People's Republic of China.
Jinan Central Hospital · CNUniversiti Malaysia Perlis · MYUniversiti Teknologi Petronas · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study correlated and quantified the expression of microRNA-155 with breast cancer to determine breast cancer progression. The target microRNA-155 sequence was identified by complementation on a capture-probe sequence-immobilized interdigitated dual electrode surface. The sensitivity was found to be 1 fM, and the limit of detection fell between 1 and 10 fM. The specific sequence selectivity with single mismatches, triple mismatches, and noncomplementary bases failed to complement the capture-probe sequence. The obtained results demonstrate the selective determination of the microRNA-155 sequence and can help to diagnose breast cancer.

Indexed as

BiosensorBreast cancerInterdigitated electrodemicroRNA-155Surface chemistry

Identifiers

PMID32523864
PMCPMC7256170
OpenAlexW3029013809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.