Evidence map›Paper›PMID 32523792›Full record

ArticleFood science and biotechnology2020

GC-MS metabolomics revealed protocatechuic acid as a cytotoxic and apoptosis-inducing compound from black rice brans.

Nancy Dewi Yuliana, Mirna Zena Tuarita, Alfi Khatib, Farida Laila, Sukarno Sukarno

Open access · greenAbstract read
In one paragraph

Article in Food science and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  6. Frontiers in nutrition · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nancy Dewi YulianaDepartment of Food Science and Technology, Faculty of Agricultural Technology, Bogor Agricultural University (IPB University), PO BOX 220, IPB Darmaga Campus, Bogor, 16002 Indonesia.ORCID 0000-0003-0249-3753
Mirna Zena TuaritaDepartment of Food Science and Technology, Faculty of Agricultural Technology, Bogor Agricultural University (IPB University), PO BOX 220, IPB Darmaga Campus, Bogor, 16002 Indonesia.
Alfi KhatibKulliyyah of Pharmacy, International Islamic University Malaysia, 25200 Kuantan, Pahang Malaysia.
Farida LailaCollege of Vocational Studies, Bogor Agricultural University (IPB University), Jalan Kumbang No. 14, Bogor, 16151 Indonesia.
Sukarno SukarnoDepartment of Food Science and Technology, Faculty of Agricultural Technology, Bogor Agricultural University (IPB University), PO BOX 220, IPB Darmaga Campus, Bogor, 16002 Indonesia.
IPB University · IDAirlangga University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GC-MS metabolomics was used to discriminate the phytochemicals profile of Indonesian white, red, and black rice brans, and Japanese white rice brans. This technique was used for the first time to identify compounds in rice brans having cytotoxic activity against WiDr colon cancer cells. Orthogonal Projection to the Latent Structure (OPLS) analysis showed that protocatechuic acid (PA) was a discriminating factor found in black rice brans which strongly correlated with its cytotoxicity (IC

Indexed as

ApoptosisCytotoxicityMetabolomicsProtocatechuic acidRice brans

Identifiers

PMID32523792
PMCPMC7256145
OpenAlexW3004530039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.