Evidence map›Paper›PMID 32523731›Full record

ArticleRegenerative biomaterials2020

Sodium alendronate loaded poly(l-lactide-

Łucja Rumian, Cornelia Wolf-Brandstetter, Sina Rößler, Katarzyna Reczyńska, Hanna Tiainen, Håvard J Haugen, Dieter Scharnweber, Elżbieta Pamuła

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Regenerative biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Recent advances in regenerative biomaterials.Regenerative biomaterials · 2022
    Review
  9. Article
  10. Review
  11. Surface-Modified Poly(l-lactide-International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Łucja RumianFaculty of Materials Science and Ceramics, Department of Biomaterials and Composites, AGH University of Science and Technology, Al. A. Mickiewicza 30, Krakow 30-059, Poland.
Cornelia Wolf-BrandstetterTechnische Universität Dresden, Institute of Materials Science, Max Bergmann Center of Biomaterials, Budapester Str. 27, Dresden 01-069, Germany.
Sina RößlerTechnische Universität Dresden, Institute of Materials Science, Max Bergmann Center of Biomaterials, Budapester Str. 27, Dresden 01-069, Germany.
Katarzyna ReczyńskaFaculty of Materials Science and Ceramics, Department of Biomaterials and Composites, AGH University of Science and Technology, Al. A. Mickiewicza 30, Krakow 30-059, Poland.
Hanna TiainenDepartment of Biomaterials, Institute for Clinical Dentistry, University of Oslo, Geitmyrsveien 71, Blindern, P.O. Box 1109, Oslo NO-0317, Norway.
Håvard J HaugenDepartment of Biomaterials, Institute for Clinical Dentistry, University of Oslo, Geitmyrsveien 71, Blindern, P.O. Box 1109, Oslo NO-0317, Norway.
Dieter ScharnweberTechnische Universität Dresden, Institute of Materials Science, Max Bergmann Center of Biomaterials, Budapester Str. 27, Dresden 01-069, Germany.
Elżbieta PamułaFaculty of Materials Science and Ceramics, Department of Biomaterials and Composites, AGH University of Science and Technology, Al. A. Mickiewicza 30, Krakow 30-059, Poland.
AGH University of Krakow · PLMax Bergmann Zentrum für Biomaterialien · DEUniversity of Oslo · NOTU Dresden · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone tissue regeneration in critical-size defects is possible after implantation of a 3D scaffold and can be additionally enhanced once the scaffold is enriched with drugs or other factors supporting bone remodelling and healing. Sodium alendronate (Aln), a widely used anti-osteoporosis drug, exhibits strong inhibitory effect on bone resorption performed by osteoclasts. Thus, we propose a new approach for the treatment of bone defects in craniofacial region combining biocompatible titanium dioxide scaffolds and poly(l-lactide-

Indexed as

ceramic scaffoldscollagencritical-size defectmicroparticlesosteoblastsosteoclastogenesispoly(l-lactide-co-glycolide)sodium alendronate

Identifiers

PMID32523731
PMCPMC7266661
OpenAlexW3014736221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.